Now showing items 1-2 of 2

    • Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium. 

      Lophatananon, A; Stewart-Brown, S; Kote-Jarai, Z; Olama, AAA; Garcia, SB; Neal, DE; Hamdy, FC; Donovan, JL; Giles, GG; Fitzgerald, LM; Southey, MC; Pharoah, P; Pashayan, N; Gronberg, H; Wiklund, F; Aly, M; Stanford, JL; Brenner, H; Dieffenbach, AK; Arndt, V; Park, JY; Lin, H-Y; Sellers, T; Slavov, C; Kaneva, R; Mitev, V; Batra, J; Spurdle, A; Clements, JA; APCB BioResource; PRACTICAL consortium; Easton, D; Eeles, RA; Muir, K (2017-08)
      Background Evidence on height and prostate cancer risk is mixed, however, recent studies with large data sets support a possible role for its association with the risk of aggressive prostate cancer.Methods We analysed data ...
    • Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association Consortium. 

      Rudolph, A; Song, M; Brook, MN; Milne, RL; Mavaddat, N; Michailidou, K; Bolla, MK; Wang, Q; Dennis, J; Wilcox, AN; Hopper, JL; Southey, MC; Keeman, R; Fasching, PA; Beckmann, MW; Gago-Dominguez, M; Castelao, JE; Guénel, P; Truong, T; Bojesen, SE; Flyger, H; Brenner, H; Arndt, V; Brauch, H; Brüning, T; Mannermaa, A; Kosma, V-M; Lambrechts, D; Keupers, M; Couch, FJ; Vachon, C; Giles, GG; MacInnis, RJ; Figueroa, J; Brinton, L; Czene, K; Brand, JS; Gabrielson, M; Humphreys, K; Cox, A; Cross, SS; Dunning, AM; Orr, N; Swerdlow, A; Hall, P; Pharoah, PDP; Schmidt, MK; Easton, DF; Chatterjee, N; Chang-Claude, J; García-Closas, M (2018-04)
      Background Polygenic risk scores (PRS) for breast cancer can be used to stratify the population into groups at substantially different levels of risk. Combining PRS and environmental risk factors will improve risk prediction; ...