Browsing Radiotherapy and Imaging by subject "Tretinoin"
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Phase I clinical trial repurposing all-trans retinoic acid as a stromal targeting agent for pancreatic cancer. (2020-09-24)Pre-clinical models have shown that targeting pancreatic stellate cells with all-trans-retinoic-acid (ATRA) reprograms pancreatic stroma to suppress pancreatic ductal adenocarcinoma (PDAC) growth. Here, in a phase Ib, dose ...