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    • Polygenic hazard score is associated with prostate cancer in multi-ethnic populations. 

      Huynh-Le, M-P; Fan, CC; Karunamuni, R; Thompson, WK; Martinez, ME; Eeles, RA; Kote-Jarai, Z; Muir, K; Schleutker, J; Pashayan, N; Batra, J; Grönberg, H; Neal, DE; Donovan, JL; Hamdy, FC; Martin, RM; Nielsen, SF; Nordestgaard, BG; Wiklund, F; Tangen, CM; Giles, GG; Wolk, A; Albanes, D; Travis, RC; Blot, WJ; Zheng, W; Sanderson, M; Stanford, JL; Mucci, LA; West, CML; Kibel, AS; Cussenot, O; Berndt, SI; Koutros, S; Sørensen, KD; Cybulski, C; Grindedal, EM; Menegaux, F; Khaw, K-T; Park, JY; Ingles, SA; Maier, C; Hamilton, RJ; Thibodeau, SN; Rosenstein, BS; Lu, Y-J; Watya, S; Vega, A; Kogevinas, M; Penney, KL; Huff, C; Teixeira, MR; Multigner, L; Leach, RJ; Cannon-Albright, L; Brenner, H; John, EM; Kaneva, R; Logothetis, CJ; Neuhausen, SL; De Ruyck, K; Pandha, H; Razack, A; Newcomb, LF; Fowke, JH; Gamulin, M; Usmani, N; Claessens, F; Gago-Dominguez, M; Townsend, PA; Bush, WS; Roobol, MJ; Parent, M-É; Hu, JJ; Mills, IG; Andreassen, OA; Dale, AM; Seibert, TM; UKGPCS collaborators; APCB (Australian Prostate Cancer BioResource); NC-LA PCaP Investigators; IMPACT Study Steering Committee and Collaborators; Canary PASS Investigators; Profile Study Steering Committee; PRACTICAL Consortium (2021-02-23)
      Genetic models for cancer have been evaluated using almost exclusively European data, which could exacerbate health disparities. A polygenic hazard score (PHS<sub>1</sub>) is associated with age at prostate cancer diagnosis ...