Unraveling complexity and leveraging opportunities in uncommon breast cancer subtypes.
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Embargo End Date
ICR Authors
Authors
Pareja, F
Bhargava, R
Borges, VF
Brogi, E
Canas Marques, R
Cardoso, F
Desmedt, C
Harigopal, M
Lakhani, SR
Lee, A
Leone, JP
Linden, H
Lord, CJ
Marchio, C
Merajver, SD
Rakha, E
Reis-Filho, JS
Richardson, A
Sawyer, E
Schedin, P
Schwartz, CJ
Tutt, A
Ueno, NT
Vincent-Salomon, A
Weigelt, B
Wen, YH
Schnitt, SJ
Oesterreich, S
Bhargava, R
Borges, VF
Brogi, E
Canas Marques, R
Cardoso, F
Desmedt, C
Harigopal, M
Lakhani, SR
Lee, A
Leone, JP
Linden, H
Lord, CJ
Marchio, C
Merajver, SD
Rakha, E
Reis-Filho, JS
Richardson, A
Sawyer, E
Schedin, P
Schwartz, CJ
Tutt, A
Ueno, NT
Vincent-Salomon, A
Weigelt, B
Wen, YH
Schnitt, SJ
Oesterreich, S
Document Type
Journal Article
Date
2025-01-24
Date Accepted
2025-01-09
Abstract
Special histologic subtypes of breast cancer (BC) exhibit unique phenotypes and molecular profiles with diagnostic and therapeutic implications, often differing in behavior and clinical trajectory from common BC forms. Novel methodologies, such as artificial intelligence may improve classification. Genetic predisposition plays roles in a subset of cases. Uncommon BC presentations like male, inflammatory and pregnancy-related BC pose challenges. Emerging therapeutic strategies targeting genetic alterations or immune microenvironment are being explored.
Citation
npj Breast Cancer, 2025, 11 (1), pp. 6 -
Source Title
npj Breast Cancer
Publisher
NATURE PORTFOLIO
ISSN
2374-4677
eISSN
2374-4677
Collections
Research Team
Gene Function
Directorate Breast Canc
Directorate Breast Canc