Adaptive radiotherapy for breast cancer.
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Embargo End Date
ICR Authors
Authors
De-Colle, C
Kirby, A
Russell, N
Shaitelman, SF
Currey, A
Donovan, E
Hahn, E
Han, K
Anandadas, CN
Mahmood, F
Lorenzen, EL
van den Bongard, D
Groot Koerkamp, ML
Houweling, AC
Nachbar, M
Thorwarth, D
Zips, D
Kirby, A
Russell, N
Shaitelman, SF
Currey, A
Donovan, E
Hahn, E
Han, K
Anandadas, CN
Mahmood, F
Lorenzen, EL
van den Bongard, D
Groot Koerkamp, ML
Houweling, AC
Nachbar, M
Thorwarth, D
Zips, D
Document Type
Journal Article
Date
2023-03-01
Date Accepted
2022-12-14
Abstract
Research in the field of local and locoregional breast cancer radiotherapy aims to maintain excellent oncological outcomes while reducing treatment-related toxicity. Adaptive radiotherapy (ART) considers variations in target and organs at risk (OARs) anatomy occurring during the treatment course and integrates these in re-optimized treatment plans. Exploiting ART routinely in clinic may result in smaller target volumes and better OAR sparing, which may lead to reduction of acute as well as late toxicities. In this review MR-guided and CT-guided ART for breast cancer patients according to different clinical scenarios (neoadjuvant and adjuvant partial breast irradiation, whole breast, chest wall and regional nodal irradiation) are reviewed and their advantages as well as challenging aspects discussed.
Citation
Clinical and Translational Radiation Oncology, 2023, 39 pp. 100564 -
Source Title
Clinical and Translational Radiation Oncology
Publisher
ELSEVIER IRELAND LTD
ISSN
2405-6308
eISSN
2405-6308
2405-6308
2405-6308