Proton Beam Therapy - the Challenges of Delivering High-quality Evidence of Clinical Benefit.
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ICR Authors
Authors
National Cancer Research Institute Clinical and Translational Radiotherapy Research Working Group (CTRad) Proton Beam Clinical Trial Strategy Group,
Document Type
Journal Article
Date
2018-05-01
Date Accepted
2018-02-19
Abstract
The use of proton beam therapy (PBT) offers the opportunity to improve greater conformality of radiotherapy treatment delivery in some patients. However, it is associated with a high capital cost and the need to build new dedicated facilities. We discuss how the global radiotherapy community can respond to the challenge of producing high-quality evidence of clinical benefit from PBT in adult patients. In the UK, the National Cancer Research Institute-funded Clinical and Radiotherapy Translational group has established the PBT Clinical Trial Strategy Group. An eight-point framework is described that can assist the development and delivery of high-quality clinical trials.
Citation
Clinical oncology (Royal College of Radiologists (Great Britain)), 2018, 30 (5), pp. 280 - 284
Source Title
Publisher
ELSEVIER SCIENCE LONDON
ISSN
0936-6555
eISSN
1433-2981
Collections
Research Team
ICR-CTSU Urology and Head and Neck Trials Team