QuPath: The global impact of an open source digital pathology system.
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ICR Authors
Authors
Humphries, MP
Maxwell, P
Salto-Tellez, M
Maxwell, P
Salto-Tellez, M
Document Type
Journal Article
Date
2021-01-29
Date Accepted
2021-01-14
Abstract
QuPath, originally created at the Centre for Cancer Research & Cell Biology at Queen's University Belfast as part of a research programme in digital pathology (DP) funded by Invest Northern Ireland and Cancer Research UK, is arguably the most wildly used image analysis software program in the world. On the back of the explosion of DP and a need to comprehensively visualise and analyse whole slides images (WSI), QuPath was developed to address the many needs associated with tissue based image analysis; these were several fold and, predominantly, translational in nature: from the requirement to visualise images containing billions of pixels from files several GBs in size, to the demand for high-throughput reproducible analysis, which the paradigm of routine visual pathological assessment continues to struggle to deliver. Resultantly, large-scale biomarker quantification must increasingly be augmented with DP. Here we highlight the impact of the open source Quantitative Pathology & Bioimage Analysis DP system since its inception, by discussing the scope of scientific research in which QuPath has been cited, as the system of choice for researchers.
Citation
Computational and structural biotechnology journal, 2021, 19 pp. 852 - 859
Source Title
Publisher
ELSEVIER
ISSN
2001-0370
eISSN
2001-0370
Collections
Research Team
Integrated Pathology
Integrated Pathology
Integrated Pathology