AI delivers Michaelis constants as fuel for genome-scale metabolic models.
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Embargo End Date
ICR Authors
Authors
Antolin, AA
Cascante, M
Cascante, M
Document Type
Journal Article
Date
2021-10-20
Date Accepted
Abstract
Michaelis constants (Km) are essential to predict the catalytic rate of enzymes, but are not widely available. A new study in PLOS Biology uses artificial intelligence (AI) to accurately predict Km on a proteome-wide scale, paving the way for dynamic, genome-wide modeling of metabolism.
Citation
PLoS biology, 2021, 19 (10), pp. e3001415 - ?
Source Title
Publisher
PUBLIC LIBRARY SCIENCE
ISSN
1544-9173
eISSN
1545-7885