Radical resection of large metastatic non-functioning pancreatic neuroendocrine carcinoma complicated by splenic vein thrombosis and sinistral portal hypertension.
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Embargo End Date
ICR Authors
Authors
Kumar, S
Raobiakady, R
Watkins, D
Terlizzo, M
Bhogal, RH
Raobiakady, R
Watkins, D
Terlizzo, M
Bhogal, RH
Document Type
Journal Article
Date
2021-04-01
Date Accepted
2021-03-03
Abstract
INTRODUCTION AND IMPORTANCE: There are limited reports in the literature of radical surgical resection for pancreatic neuroendocrine carcinoma (PNEC). In patients with non-functioning PNEC (NF-PNEC) within the tail of the pancreas tumours can cause splenic vein thrombosis (SVT) and subsequent sinitral portal hypertension (SPH). Radical surgical resection in such patients with concomitant liver metastasis has not previously been reported. CASE PRESENTATION: We present a 67-year old female patient who presented with a large NF-PNEC within the tail of the pancreas with liver metastasis. We performed a distal pancreatectomy, splenectomy, partial gastrectomy and liver resection to achieve radical resecton. DISCUSSION: All patients with NF-PNEC within the tail of the pancreatic should be considered for radical surgical resection. In the presence of multi-visceral involvement and complications such as SVT and/or SPH multi-speciality surgical expertise is likely to be required. CONCLUSION: Radical multi-visceral resection for large NF-PNEC can be safely performed in the presence of SVT and SPH.
Citation
International Journal of Surgery Case Reports, 2021, 81 pp. 105724 -
Source Title
International Journal of Surgery Case Reports
Publisher
Ovid Technologies (Wolters Kluwer Health)
ISSN
2210-2612
eISSN
2210-2612
2210-2612
2210-2612
Collections
Research Team
Gastrointestinal Unit