Management of the vertebrae as an organ at risk in paediatric radiotherapy clinical trials: Initial QUARTET experience.
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Embargo End Date
ICR Authors
Authors
Turcas, A
Kelly, SM
Bernier-Chastagner, V
Bolle, S
Cameron, A
Corning, C
Clementel, E
Dieckmann, K
Davila Fajardo, R
Gaze, MN
Laprie, A
Magelssen, H
Meroni, S
Pignoli, E
Safwat, A
Scarzello, G
Talbot, J
Timmermann, B
Boterberg, T
Mandeville, HC
Kelly, SM
Bernier-Chastagner, V
Bolle, S
Cameron, A
Corning, C
Clementel, E
Dieckmann, K
Davila Fajardo, R
Gaze, MN
Laprie, A
Magelssen, H
Meroni, S
Pignoli, E
Safwat, A
Scarzello, G
Talbot, J
Timmermann, B
Boterberg, T
Mandeville, HC
Document Type
Journal Article
Date
2023-10-01
Date Accepted
2023-07-10
Abstract
Irradiation of the vertebrae in prepubertal patients, if non-homogenous, can result in future growth deformities including kyphoscoliosis. Vertebral delineation and dosimetry were assessed for 101 paediatric cases reviewed within QUARTET-affiliated trials. Despite the availability of published consensus guidelines, a high variability in vertebral delineation was observed, with impact on dosimetry.
Citation
Radiotherapy and Oncology, 2023, 187 pp. 109810 -
Source Title
Radiotherapy and Oncology
Publisher
ELSEVIER IRELAND LTD
ISSN
0167-8140
eISSN
1879-0887
1879-0887
1879-0887
Collections
Research Team
Paed & Adolesc Radiother