Recognising the challenges of implementing multi-centre adaptive plan of the day radiotherapy.
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ICR Authors
Authors
Webster, A
McNair, HA
Hansen, VN
Lewis, R
Patel, E
Miles, E
Hall, E
Hafeez, S
Huddart, R
RAIDER, HYBRID Trial Management Groups,
McNair, HA
Hansen, VN
Lewis, R
Patel, E
Miles, E
Hall, E
Hafeez, S
Huddart, R
RAIDER, HYBRID Trial Management Groups,
Document Type
Journal Article
Date
2022-03-01
Date Accepted
2022-01-26
Abstract
Two multicentre adaptive radiotherapy trials utilising Plan of the Day (PoD) with a library of plans were introduced in 35 centres. The common issues that arose from all centres when introducing PoD were collated retrospectively, through reviewing the data pertaining to the pre-trial and on-trial quality assurance programme. It was found that 1,295 issues arose when introducing PoD in outlining, planning, treatment delivery i.e., PoD selection, and in the overall process of delivering PoD. There was no difference in the number of issues that arose from pre-trial to on-trial. Thus, it is recommended that the implementation of PoD is supported by guidance, reviews, and continuous monitoring.
Citation
Technical Innovations & Patient Support in Radiation Oncology
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Research Team
Clinical Trials & Statistics Unit