Cancer heterogeneity and imaging.
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Embargo End Date
ICR Authors
Authors
O'Connor, JPB
Document Type
Journal Article
Date
2017-04-01
Date Accepted
2016-10-03
Abstract
There is interest in identifying and quantifying tumor heterogeneity at the genomic, tissue pathology and clinical imaging scales, as this may help better understand tumor biology and may yield useful biomarkers for guiding therapy-based decision making. This review focuses on the role and value of using x-ray, CT, MRI and PET based imaging methods that identify, measure and map tumor heterogeneity. In particular we highlight the potential value of these techniques and the key challenges required to validate and qualify these biomarkers for clinical use.
Citation
Seminars in cell & developmental biology, 2017, 64 pp. 48 - 57
Source Title
Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
ISSN
1084-9521
eISSN
1096-3634
Collections
Research Team
Quantitative Biomedical Imaging