New Prognostic Biomarkers in Metastatic Castration-Resistant Prostate Cancer.
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ICR Authors
Authors
Conteduca, V
Mosca, A
Brighi, N
de Giorgi, U
Rescigno, P
Mosca, A
Brighi, N
de Giorgi, U
Rescigno, P
Document Type
Journal Article
Date
2021-01-19
Date Accepted
2021-01-13
Date Available
2021-04-09T14:00:29Z
Abstract
Prostate cancer is one of the most frequent cancers in men and is a common cause of cancer-related death. Despite significant progress in the diagnosis and treatment of this tumor, patients who relapse after radical treatments inevitably develop metastatic disease. Patient stratification is therefore key in this type of cancer, and there is an urgent need for prognostic biomarkers that can define patients' risk of cancer-related death. In the last 10 years, multiple prognostic factors have been identified and studied. Here, we review the literature available and discuss the most common aberrant genomic pathways in metastatic castration-resistant prostate cancer shown to have a prognostic relevance in this setting.
Citation
Cells, 2021, 10 (1)
Source Title
Publisher
MDPI
ISSN
2073-4409
eISSN
2073-4409
Collections
Research Team
Prostate Cancer Targeted Therapy Group
Prostate Cancer Targeted Therapy Group
Prostate Cancer Targeted Therapy Group