Fever of Unknown Origin: the Value of FDG-PET/CT.
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Embargo End Date
ICR Authors
Authors
Kouijzer, IJE
Mulders-Manders, CM
Bleeker-Rovers, CP
Oyen, WJG
Mulders-Manders, CM
Bleeker-Rovers, CP
Oyen, WJG
Document Type
Journal Article
Date
2018-03
Date Accepted
2017-11-23
Abstract
Fever of unknown origin (FUO) is commonly defined as fever higher than 38.3°C on several occasions during at least 3 weeks with uncertain diagnosis after a number of obligatory investigations. The differential diagnosis of FUO can be subdivided in four categories: infections, malignancies, noninfectious inflammatory diseases, and miscellaneous causes. In most cases of FUO, there is an uncommon presentation of a common disease. FDG-PET/CT is a sensitive diagnostic technique for the evaluation of FUO by facilitating anatomical localization of focally increased FDG uptake, thereby guiding further diagnostic tests to achieve a final diagnosis. FDG-PET/CT should become a routine procedure in the workup of FUO when diagnostic clues are absent. FDG-PET/CT appears to be a cost-effective routine imaging technique in FUO by avoiding unnecessary investigations and reducing the duration of hospitalization.
Citation
Seminars in nuclear medicine, 2018, 48 (2), pp. 100 - 107
Source Title
Publisher
ISSN
0001-2998
eISSN
1558-4623
Collections
Research Team
Translational Molecular Imaging