canSAR: update to the cancer translational research and drug discovery knowledgebase.
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Authors
Coker, EA
Mitsopoulos, C
Tym, JE
Komianou, A
Kannas, C
Di Micco, P
Villasclaras Fernandez, E
Ozer, B
Antolin, AA
Workman, P
Al-Lazikani, B
Mitsopoulos, C
Tym, JE
Komianou, A
Kannas, C
Di Micco, P
Villasclaras Fernandez, E
Ozer, B
Antolin, AA
Workman, P
Al-Lazikani, B
Document Type
Journal Article
Date
2019-01-08
Date Accepted
2018-11-26
Abstract
canSAR (http://cansar.icr.ac.uk) is a public, freely available, integrative translational research and drug discovery knowlegebase. canSAR informs researchers to help solve key bottlenecks in cancer translation and drug discovery. It integrates genomic, protein, pharmacological, drug and chemical data with structural biology, protein networks and unique, comprehensive and orthogonal 'druggability' assessments. canSAR is widely used internationally by academia and industry. Here we describe major enhancements to canSAR including new and expanded data. We also describe the first components of canSARblack-an advanced, responsive, multi-device compatible redesign of canSAR with a question-led interface.
Citation
Nucleic acids research, 2019, 47 (D1), pp. D917 - D922
Source Title
Publisher
OXFORD UNIV PRESS
ISSN
0305-1048
eISSN
1362-4962
Collections
Research Team
Computational Biology and Chemogenomics