EANM enabling guide: how to improve the accessibility of clinical dosimetry.
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Embargo End Date
ICR Authors
Authors
Gear, J
Stokke, C
Terwinghe, C
Gnesin, S
Sandström, M
Tran-Gia, J
Cremonesi, M
Cicone, F
Verburg, F
Hustinx, R
Giovanella, L
Herrmann, K
Gabiña, PM
Stokke, C
Terwinghe, C
Gnesin, S
Sandström, M
Tran-Gia, J
Cremonesi, M
Cicone, F
Verburg, F
Hustinx, R
Giovanella, L
Herrmann, K
Gabiña, PM
Document Type
Journal Article
Date
2023-04-22
Date Accepted
2023-04-04
Abstract
Dosimetry can be a useful tool for personalization of molecular radiotherapy (MRT) procedures, enabling the continuous development of theranostic concepts. However, the additional resource requirements are often seen as a barrier to implementation. This guide discusses the requirements for dosimetry and demonstrates how a dosimetry regimen can be tailored to the available facilities of a centre. The aim is to help centres wishing to initiate a dosimetry service but may not have the experience or resources of some of the more established therapy and dosimetry centres. The multidisciplinary approach and different personnel requirements are discussed and key equipment reviewed example protocols demonstrating these factors are given in the supplementary material for the main therapies carried out in nuclear medicine, including [131I]-NaI for benign thyroid disorders, [177Lu]-DOTATATE and 131I-mIBG for neuroendocrine tumours and [90Y]-microspheres for unresectable hepatic carcinoma.
Citation
European Journal of Nuclear Medicine and Molecular Imaging, 2023,
Source Title
European Journal of Nuclear Medicine and Molecular Imaging
Publisher
SPRINGER
ISSN
1619-7070
eISSN
1619-7089
1619-7089
1619-7089