Application of Liquid Biopsies in Cancer Targeted Therapy.
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ICR Authors
Authors
Sumanasuriya, S
Lambros, MB
de Bono, JS
Lambros, MB
de Bono, JS
Document Type
Journal Article
Date
2017-11-01
Date Accepted
2017-06-01
Date Available
Abstract
As a growing body of evidence demonstrates intertumoral and intratumoral heterogeneity and clonal evolution, both during carcinogenesis and also throughout treatment resulting in acquired drug resistance, the utility of blood-based assays or "liquid biopsies" is becoming increasingly recognized in clinical practice and trial design. "Liquid biopsies" provide a less invasive approach to the current gold standard of interrogating tumors by tissue biopsies, which are frequently unfeasible, associated with morbidity, and cannot be performed as often.
Citation
Clinical pharmacology and therapeutics, 2017, 102 (5), pp. 745 - 747
DOI
Source Title
Publisher
WILEY
ISSN
0009-9236
eISSN
1532-6535
Collections
Research Team
Cancer Biomarkers
Prostate Cancer Targeted Therapy Group
Prostate Cancer Targeted Therapy Group