Class(y) Dissection of BRAF Heterogeneity: Beyond Non-V600.
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Embargo End Date
ICR Authors
Authors
Fontana, E
Valeri, N
Valeri, N
Document Type
Journal Article
Date
2019-12-01
Date Accepted
2019-10-01
Abstract
Different classes of BRAF mutations are present in colorectal and other cancers. Non-V600 mutations are rare; however, their detection rate will increase as the use of next-generation sequencing ramps up quickly in clinical practice. Different biochemical signaling pathways are active in non-V600 BRAF-mutant cancers and may affect treatment response.See related article by Yaeger et al., p. 7089.
Citation
Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 25 (23), pp. 6896 - 6898
Source Title
Publisher
AMER ASSOC CANCER RESEARCH
ISSN
1078-0432
eISSN
1557-3265
Collections
Research Team
Gastrointestinal Cancer Biology and Genomics
Systems and Precision Cancer Medicine
Systems and Precision Cancer Medicine