Love laughs at Locksmiths: Ubiquitylation of p62 unlocks its autophagy receptor potential.
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Embargo End Date
ICR Authors
Authors
Conway, O
Kirkin, V
Kirkin, V
Document Type
Journal Article
Date
2017-05-01
Date Accepted
2017-05-01
Abstract
The multimodular adapter p62/sequestosome-1 plays prominent roles in physiology and disease by mediating cell signaling and cargo degradation. The work by Peng et al. published recently in Cell Research provides mechanistic insights into activation of its autophagy receptor function critical for maintaining cell homeostasis during various forms of stress.
Citation
Cell research, 2017, 27 (5), pp. 595 - 597
Source Title
Publisher
INST BIOCHEMISTRY & CELL BIOLOGY
ISSN
1001-0602
eISSN
1748-7838
Collections
Research Team
Cell Death and Immunity
Cancer Pharmacology & Stress Response (CPSR)
Cancer Pharmacology & Stress Response (CPSR)