Fragment growing to retain or alter the selectivity of anchored kinase hinge-binding fragments
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Embargo End Date
ICR Authors
Authors
Allen, CE
Welford, AJ
Matthews, TP
Caldwell, JJ
Collins, I
Welford, AJ
Matthews, TP
Caldwell, JJ
Collins, I
Document Type
Journal Article
Date
2014-01-01
Date Accepted
Abstract
<p>The selectivity patterns of kinase hinge-binding fragments can be retained during fragment growing, suggesting a new way to control poly-pharmacology.</p>
Citation
MEDCHEMCOMM, 2014, 5 (2), pp. 180 - 185 (6)
Source Title
Publisher
ROYAL SOC CHEMISTRY
ISSN
2040-2503
eISSN
2040-2511
Collections
Research Team
Medicinal Chemistry 2