CancerGD: a resource for identifying and interpreting genetic dependencies in cancer
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Bridgett, S
Campbell, J
Lord, C
Ryan, C
Campbell, J
Lord, C
Ryan, C
Document Type
Journal Article
Date
2016-10-26
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Abstract
Abstract Genes whose function is selectively essential in the presence of cancer associated genetic aberrations represent promising targets for the development of precision therapeutics. Here we present CancerGD ( www.cancergd.org ), a resource that integrates genotypic profiling with large-scale loss-of-function genetic screens in tumor cell lines to identify such genetic dependencies. CancerGD provides tools for searching, visualizing, and interpreting these genetic dependencies through the integration of functional interaction networks.
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2016
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Gene Function