Gastrointestinal tissue-based molecular biomarkers: a practical categorisation based on the 2019 World Health Organization classification of epithelial digestive tumours.
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Embargo End Date
ICR Authors
Authors
Quezada-Marín, JI
Lam, AK
Ochiai, A
Odze, RD
Washington, KM
Fukayama, M
Rugge, M
Klimstra, DS
Nagtegaal, ID
Tan, P-H
Arends, MJ
Goldblum, JR
Cree, IA
Salto-Tellez, M
Lam, AK
Ochiai, A
Odze, RD
Washington, KM
Fukayama, M
Rugge, M
Klimstra, DS
Nagtegaal, ID
Tan, P-H
Arends, MJ
Goldblum, JR
Cree, IA
Salto-Tellez, M
Document Type
Journal Article
Date
2020-09-01
Date Accepted
2020-04-15
Abstract
Molecular biomarkers have come to constitute one of the cornerstones of oncological pathology. The method of classification not only directly affects the manner in which patients are diagnosed and treated, but also guides the development of drugs and of artificial intelligence tools. The aim of this article is to organise and update gastrointestinal molecular biomarkers in order to produce an easy-to-use guide for routine diagnostics. For this purpose, we have extracted and reorganised the molecular information on epithelial neoplasms included in the 2019 World Health Organization classification of tumours. Digestive system tumours, 5th edn.
Citation
Histopathology, 2020, 77 (3), pp. 340 - 350
Source Title
Publisher
WILEY
ISSN
0309-0167
eISSN
1365-2559
Collections
Research Team
Integrated Pathology