Arresting metastasis within the microcirculation.
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Embargo End Date
ICR Authors
Authors
Varotsos Vrynas, A
Perea Paizal, J
Bakal, C
Au, SH
Perea Paizal, J
Bakal, C
Au, SH
Document Type
Journal Article
Date
2021-07-09
Date Accepted
2021-06-02
Abstract
The behaviour of circulating tumour cells in the microcirculation remains poorly understood. Growing evidence suggests that biomechanical adaptations and interactions with blood components, i.e. immune cells and platelets within capillary beds, may add more complexity to CTCs journey towards metastasis. Revisiting how these mediators impact the ability of circulating tumour cells to survive and metastasise, will be vital to understand the role of microcirculation and advance our knowledge on metastasis.
Citation
Clinical and Experimental Metastasis, 2021, 38 (4), pp. 337 - 342
Rights
Source Title
Clinical and Experimental Metastasis
Publisher
SPRINGER
ISSN
0262-0898
eISSN
1573-7276
Collections
Research Team
Dynamical Cell Systems