Browsing by author "Mittnacht, Sibylle"

Now showing items 1-3 of 3

    • Heterogeneous proliferative potential in regenerative adult newt cardiomyocytes. 

      Bettencourt-Dias, M; Mittnacht, S; Brockes, JP (COMPANY BIOLOGISTS LTD, 2003-10-01)
      Adult newt cardiomyocytes, in contrast to their mammalian counterparts, can proliferate after injury and contribute to the functional regeneration of the heart. In order to understand the mechanisms underlying this plasticity ...

    • Mechanism-based screen establishes signalling framework for DNA damage-associated G1 checkpoint response. 

      Richardson, E; Stockwell, SR; Li, H; Aherne, W; Cuomo, ME; et al. (PUBLIC LIBRARY SCIENCE, 2012-02-27)
      DNA damage activates checkpoint controls which block progression of cells through the division cycle. Several different checkpoints exist that control transit at different positions in the cell cycle. A role for checkpoint ...

    • Role of the Tripartite Motif Protein 27 in Cancer Development 

      Zoumpoulidou, G; Broceno, C; Li, H; Bird, D; Thomas, G; et al. (OXFORD UNIV PRESS INC, 2012-06-01)
      Background The tripartite motif family protein 27 (TRIM27) is a transcriptional repressor that interacts with, and attenuates senescence induction by, the retinoblastoma-associated protein (RB1). High expression of TRIM27 ...