This is a database of the academic work published by our staff and students. The full text of many of our journal articles is available free of charge from this website.
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Gene-environment dependence creates spurious gene-environment interaction.
(2014-09)Gene-environment interactions have the potential to shed light on biological processes leading to disease and to improve the accuracy of epidemiological risk models. However, relatively few such interactions have yet been ... -
Systematic evaluation of the prognostic impact and intratumour heterogeneity of clear cell renal cell carcinoma biomarkers.
(2014-11)BACKGROUND:Candidate biomarkers have been identified for clear cell renal cell carcinoma (ccRCC) patients, but most have not been validated. OBJECTIVE:To validate published ccRCC prognostic biomarkers in an independent ... -
Candidate gene-environment interactions in breast cancer.
(2014-10-17)Gene-environment interactions have the potential to shed light on biological processes leading to disease, identify individuals for whom risk factors are most relevant, and improve the accuracy of epidemiological risk ... -
Sex specific retinoic acid signaling is required for the initiation of urogenital sinus bud development.
(2014-11)The mammalian urogenital sinus (UGS) develops in a sex specific manner, giving rise to the prostate in the male and the sinus vagina in the embryonic female. Androgens, produced by the embryonic testis, have been shown to ... -
Targeting molecular addictions in cancer.
(2014-11)Cancer cells depend on a finite number of critical signals for their survival. Oncogene addiction, that is, the acquired dependence of a cancer cell on the activity of a single oncogenic gene product, has been the basis ...
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