This is a database of the academic work published by our staff and students. The full text of many of our journal articles is available free of charge from this website.
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Investigating acute cellular responses to elevated APOBEC3B expression
(2021-09-30)The cytosine deaminase APOBEC3B (A3B) functions as part of innate immunity by mutating viral DNA and preventing replication. Large-scale genome sequencing studies and examination of expression levels have identified mutations ... -
The effects of oncolytic Maraba virus (MG1) in advanced non-small cell lung cancer
(2021-08-31)Lung cancer is responsible for the highest cancer mortality worldwide. The prognosis for patients with advanced disease remains poor with five-year overall survival of <10%, highlighting the urgent unmet need for novel ... -
Molecular mechanisms of PARP inhibitor sensitivity in primary triple negative breast cancer
(2021-08-31)Triple negative breast cancer (TNBC) encompasses molecularly different subgroups, with a subgroup harbouring evidence of defective homologous recombination (HR) DNA repair. At present there are no biomarkers available in ... -
Functional characterisation of EGFR mutations in cancer
(2021-08-31)Large-scale pan-cancer sequencing of tumour samples has identified a plethora of epidermal growth factor (EGFR) mutations along the full length of the gene. However, clinical studies have demonstrated that distinct mutations ...
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