This is a database of the academic work published by our staff and students. The full text of many of our journal articles is available free of charge from this website.
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Inactivating NF1 mutations are enriched in advanced breast cancer and contribute to endocrine therapy resistance.
(2019-10-07)PURPOSE: Advanced breast cancer (ABC) has not been subjected to the same degree of molecular scrutiny as early primary cancer. Breast cancer evolves with time and under the selective pressure of treatment, with the potential ... -
Early enrichment of ESR1 mutations and the impact on gene expression in pre-surgical primary breast cancer treated with aromatase inhibitors.
(2019-09-23)PURPOSE: To investigate the presence of ESR1 mutation in primary oestrogen-receptor positive breast cancer (ER+BC) treated with extended (>4 weeks) neoadjuvant (pre-surgical) aromatase inhibitor (NAI) therapy and to identify ... -
A method to verify sections of arc during intrafraction portal dosimetry for prostate VMAT.
(2019-10-16)This study investigates the use of a running sum of images during segment-resolved intrafraction portal dosimetry for volumetric modulated arc therapy (VMAT), so as to alert the operator to an error before it becomes ... -
Treatment planning optimization with beam motion modelling for dynamic arc delivery of SBRT using Cyberknife with multileaf collimation.
(2019-10-06)PURPOSE: The use of dynamic arcs for delivery of stereotactic body radiation therapy (SBRT) on Cyberknife is investigated, with a view to improving treatment times. This study investigates the required modelling of robot ...
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