This is a database of the academic work published by our staff and students. The full text of many of our journal articles is available free of charge from this website. Older publications are currently available at https://publications.icr.ac.uk

  • Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study. 

    Dimitrakopoulou, VI; Tsilidis, KK; Haycock, PC; Dimou, NL; Al-Dabhani, K; Martin, RM; Lewis, SJ; Gunter, MJ; Mondul, A; Shui, IM; Theodoratou, E; Nimptsch, K; Lindström, S; Albanes, D; Kühn, T; Key, TJ; Travis, RC; Vimaleswaran, KS; GECCO Consortium; PRACTICAL Consortium; GAME-ON Network (CORECT, DRIVE, ELLIPSE, FOCI-OCAC, TRICL-ILCCO); Kraft, P; Pierce, BL; Schildkraut, JM (2017-10-31)
    Objective To determine if circulating concentrations of vitamin D are causally associated with risk of cancer.Design Mendelian randomisation study.Setting Large genetic epidemiology networks (the Genetic Associations and ...
  • Circulating vitamin D concentrations and risk of breast and prostate cancer: a Mendelian randomization study. 

    Jiang, X; Dimou, NL; Al-Dabhani, K; Lewis, SJ; Martin, RM; Haycock, PC; Gunter, MJ; Key, TJ; Eeles, RA; Muir, K; Neal, D; Giles, GG; Giovannucci, EL; Stampfer, M; Pierce, BL; Schildkraut, JM; Warren Andersen, S; Thompson, D; Zheng, W; Kraft, P; Tsilidis, KK (2018-12-28)
    Background: Observational studies have suggested an association between circulating vitamin D concentrations [25(OH)D] and risk of breast and prostate cancer, which was not supported by a recent Mendelian randomization ...
  • LONG-NONCODING RNAs in gastroesophageal cancers. 

    Fanelli, GN; Gasparini, P; Coati, I; Cui, R; Pakula, H; Chowdhury, B; Valeri, N; Loupakis, F; Kupcinskas, J; Cappellesso, R; Fassan, M (2018-12)
    Despite continuing improvements in multimodal therapies, gastro-esophageal malignances remain widely prevalent in the population and is characterized by poor overall and disease-free survival rates. Due to the lack of ...
  • Genomic loss of heterozygosity and survival in the REAL3 trial. 

    Smyth, EC; Cafferkey, C; Loehr, A; Waddell, T; Begum, R; Peckitt, C; Harding, TC; Nguyen, M; Okines, AF; Raponi, M; Rao, S; Watkins, D; Starling, N; Middleton, GW; Wadsley, J; Mansoor, W; Crosby, T; Wotherspoon, A; Chau, I; Cunningham, D (2018-11-30)
    Background: Homologous recombination deficiency (HRD) measured using a genomic signature for loss of heterozygosity (LOH) predicts benefit from rucaparib in ovarian cancer. We hypothesized that some oesophagogastric cancers ...
  • A seven-Gene Signature assay improves prognostic risk stratification of perioperative chemotherapy treated gastroesophageal cancer patients from the MAGIC trial. 

    Smyth, EC; Nyamundanda, G; Cunningham, D; Fontana, E; Ragulan, C; Tan, IB; Lin, SJ; Wotherspoon, A; Nankivell, M; Fassan, M; Lampis, A; Hahne, JC; Davies, AR; Lagergren, J; Gossage, JA; Maisey, N; Green, M; Zylstra, JL; Allum, WH; Langley, RE; Tan, P; Valeri, N; Sadanandam, A (2018-12-01)
    Background: Following neoadjuvant chemotherapy for operable gastroesophageal cancer, lymph node metastasis is the only validated prognostic variable; however, within lymph node groups there is still heterogeneity with risk ...

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