• Radiotherapy to the primary tumour for newly diagnosed, metastatic prostate cancer (STAMPEDE): a randomised controlled phase 3 trial. 

  Parker, CC; James, ND; Brawley, CD; Clarke, NW; Hoyle, AP; Ali, A; Ritchie, AWS; Attard, G; Chowdhury, S; Cross, W; Dearnaley, DP; Gillessen, S; Gilson, C; Jones, RJ; Langley, RE; Malik, ZI; Mason, MD; Matheson, D; Millman, R; Russell, JM; Thalmann, GN; Amos, CL; Alonzi, R; Bahl, A; Birtle, A; Din, O; Douis, H; Eswar, C; Gale, J; Gannon, MR; Jonnada, S; Khaksar, S; Lester, JF; O'Sullivan, JM; Parikh, OA; Pedley, ID; Pudney, DM; Sheehan, DJ; Srihari, NN; Tran, ATH; Parmar, MKB; Sydes, MR; Systemic Therapy for Advanced or Metastatic Prostate cancer: Evaluation of Drug Efficacy (STAMPEDE) investigators (2018-12-01)

  BACKGROUND: Based on previous findings, we hypothesised that radiotherapy to the prostate would improve overall survival in men with metastatic prostate cancer, and that the benefit would be greatest in patients with a low ...
• Comparison of prostate delineation on multimodality imaging for MR-guided radiotherapy. 

  Pathmanathan, AU; McNair, HA; Schmidt, MA; Brand, DH; Delacroix, L; Eccles, CL; Gordon, A; Herbert, T; van As, NJ; Huddart, RA; Tree, AC (2019-01-24)

  OBJECTIVE:: With increasing incorporation of MRI in radiotherapy, we investigate two MRI sequences for prostate delineation in radiographer-led image guidance. METHODS:: Five therapeutic radiographers contoured the prostate ...
• 'Relationship between thermal dose and cell death for "rapid" ablative and "slow" hyperthermic heating'. 

  Mouratidis, PXE; Rivens, I; Civale, J; Symonds-Tayler, R; Ter Haar, G (2019-01-31)

  AIM: Thermal isoeffective dose (TID) has not been convincingly validated for application to predict biological effects from rapid thermal ablation (e.g., using >55 °C). This study compares the classical method of quantifying ...
• Trans-abdominal in vivo placental vessel occlusion using High Intensity Focused Ultrasound. 

  Shaw, CJ; Rivens, I; Civale, J; Botting, KJ; Ter Haar, G; Giussani, DA; Lees, CC (2018-09-11)

  Pre-clinically, High Intensity Focused Ultrasound (HIFU) has been shown to safely and effectively occlude placental blood vessels in the acute setting, when applied through the uterus. However, further development of the ...
• Synthesis of a benzoxazinthione derivative of tanaproget and pharmacological evaluation for PET imaging of PR expression 

  Allott, L; Miranda, C; Hayes, A; Raynaud, F; Cawthorne, C; Smith, G (Springer Nature, 2019-12)

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