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  • Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study. 

    Dimitrakopoulou, VI; Tsilidis, KK; Haycock, PC; Dimou, NL; Al-Dabhani, K; Martin, RM; Lewis, SJ; Gunter, MJ; Mondul, A; Shui, IM; Theodoratou, E; Nimptsch, K; Lindström, S; Albanes, D; Kühn, T; Key, TJ; Travis, RC; Vimaleswaran, KS; GECCO Consortium; PRACTICAL Consortium; GAME-ON Network (CORECT, DRIVE, ELLIPSE, FOCI-OCAC, TRICL-ILCCO); Kraft, P; Pierce, BL; Schildkraut, JM (2017-10-31)
    Objective To determine if circulating concentrations of vitamin D are causally associated with risk of cancer.Design Mendelian randomisation study.Setting Large genetic epidemiology networks (the Genetic Associations and ...
  • Circulating vitamin D concentrations and risk of breast and prostate cancer: a Mendelian randomization study. 

    Jiang, X; Dimou, NL; Al-Dabhani, K; Lewis, SJ; Martin, RM; Haycock, PC; Gunter, MJ; Key, TJ; Eeles, RA; Muir, K; Neal, D; Giles, GG; Giovannucci, EL; Stampfer, M; Pierce, BL; Schildkraut, JM; Warren Andersen, S; Thompson, D; Zheng, W; Kraft, P; Tsilidis, KK (2018-12-28)
    Background: Observational studies have suggested an association between circulating vitamin D concentrations [25(OH)D] and risk of breast and prostate cancer, which was not supported by a recent Mendelian randomization ...
  • LONG-NONCODING RNAs in gastroesophageal cancers. 

    Fanelli, GN; Gasparini, P; Coati, I; Cui, R; Pakula, H; Chowdhury, B; Valeri, N; Loupakis, F; Kupcinskas, J; Cappellesso, R; Fassan, M (2018-12)
    Despite continuing improvements in multimodal therapies, gastro-esophageal malignances remain widely prevalent in the population and is characterized by poor overall and disease-free survival rates. Due to the lack of ...
  • Genomic loss of heterozygosity and survival in the REAL3 trial. 

    Smyth, EC; Cafferkey, C; Loehr, A; Waddell, T; Begum, R; Peckitt, C; Harding, TC; Nguyen, M; Okines, AF; Raponi, M; Rao, S; Watkins, D; Starling, N; Middleton, GW; Wadsley, J; Mansoor, W; Crosby, T; Wotherspoon, A; Chau, I; Cunningham, D (2018-11-30)
    Background: Homologous recombination deficiency (HRD) measured using a genomic signature for loss of heterozygosity (LOH) predicts benefit from rucaparib in ovarian cancer. We hypothesized that some oesophagogastric cancers ...

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