This is the ICR’s publications repository, an open access repository of full-text research articles and theses by ICR staff and students.
Recent Submissions
Item OCAMS-RASR - OutComes in patients with brAin MetastaseS receiving stereotactic RAdio-SuRgery(Institute of Cancer Research (University Of London), 2026-06-09)I hypothesise that outcomes after stereotactic radiosurgery (SRS) for patients with brain metastases (BMs) can be better predicted through understanding the relationship with tumour characteristics, dosimetry and radiological data. I aim to model the dose-response relationship for i) local tumour control in patients undergoing SRS for BMs; ii) to assess the relationship between tumour histology and BM vascularity, as defined on Contrast- Clearance-Analysis (CCA) MRI, and explore if CCA-MRI can help predict radiological outcomes; iii) to examine BM number as a prognostic variable for survival, focusing on those with >10BMs; and iv) to report the incidence of, and identify risk factors for, seizures after SRS. Data comes from 2 sources, i) a prospective observational study following-up patients with BMs after SRS and ii) a large prospectively collected single-institution database of patients undergoing SRS. BMs incidence is increasing, and survival is improving. Better understanding the factors which affect tumour response, patient survival and treatment-related toxicities after SRS could improve outcomes for patients with BMs
Communities in The ICR Publications Repository
Select a community to browse its collections.