Browsing by author "Jorgensen, Claus"
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PKA-regulated VASP phosphorylation promotes extrusion of transformed cells from the epithelium.
Anton, KA; Sinclair, J; Ohoka, A; Kajita, M; Ishikawa, S; et al. (COMPANY OF BIOLOGISTS LTD, 2014-08-15)At the early stages of carcinogenesis, transformation occurs in single cells within tissues. In an epithelial monolayer, such mutated cells are recognized by their normal neighbors and are often apically extruded. The ...