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    • Focal amplification of the androgen receptor gene in hormone-naive human prostate cancer 

      Merson, S; Yang, ZH; Brewer, D; Olmos, D; Eichholz, A; McCarthy, F; Fisher, G; Kovacs, G; Berney, DM; Foster, CS; Moller, H; Scardino, P; Cuzick, J; Cooper, CS; Clark, JP; Grp, TP (NATURE PUBLISHING GROUP, 2014-03-18)
      Background: Androgen receptor (AR)-gene amplification, found in 20-30% of castration-resistant prostate cancer (CRPCa) is proposed to develop as a consequence of hormone-deprivation therapy and be a prime cause of treatment ...