Browsing by author "Faisal, Amir"
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Cisplatin induces apoptosis through the ERK-p66shc pathway in renal proximal tubule cells
(ELSEVIER IRELAND LTD, 2010-11)The extracellular signal-regulated kinase (ERK) has been shown to mediate cisplatin (CP)-induced toxicity to renal proximal tubule cells. Here, we demonstrate that ERK serves as the kinase that phosphorylates the pro-apoptotic ... -
p66SHC-mediated mitochondrial dysfunction in renal proximal tubule cells during oxidative injury
(AMER PHYSIOLOGICAL SOC, 2010-05)Arany I, Faisal A, Clark JS, Vera T, Baliga R, Nagamine Y. p66SHC-mediated mitochondrial dysfunction in renal proximal tubule cells during oxidative injury. Am J Physiol Renal Physiol 298: F1214-F1221, 2010. First published ...