Browsing by author "Smalley, Matthew"
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Mig6 Is a Sensor of EGF Receptor Inactivation that Directly Activates c-Abl to Induce Apoptosis during Epithelial Homeostasis
Hopkins, S; Linderoth, E; Hantschel, O; Suarez-Henriques, P; Pilia, G; et al. (CELL PRESS, 2012-09-11)A fundamental aspect of epithelial homeostasis is the dependence on specific growth factors for cell survival, yet the underlying mechanisms remain obscure. We found an “inverse” mode of receptor tyrosine kinase signaling ...