Browsing by author "Beloueche-Babari, Mounia"
Now showing items 1-2 of 2
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Detecting human melanoma cell re-differentiation following BRAF or heat shock protein 90 inhibition using photoacoustic and magnetic resonance imaging.
Shah, A; Delgado-Goni, T; Casals Galobart, T; Wantuch, S; Jamin, Y; et al. (NATURE PUBLISHING GROUP, 2017-08-15)Targeted therapies specific to the BRAF-MEK-ERK signaling pathway have shown great promise in the treatment of malignant melanoma in the last few years, with these drugs now commonly used in clinic. Melanoma cells treated ... -
The BRAF Inhibitor Vemurafenib Activates Mitochondrial Metabolism and Inhibits Hyperpolarized Pyruvate-Lactate Exchange in BRAF-Mutant Human Melanoma Cells.
Delgado-Goni, T; Miniotis, MF; Wantuch, S; Parkes, HG; Marais, R; et al. (AMER ASSOC CANCER RESEARCH, 2016-12-01)Understanding the impact of BRAF signaling inhibition in human melanoma on key disease mechanisms is important for developing biomarkers of therapeutic response and combination strategies to improve long-term disease ...