Browsing by author "Paterson, Hugh"
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Monophosphothreonyl extracellular signal-regulated kinases 1 and 2 (ERK1/2) are formed endogenously in intact cardiac myocytes and are enzymically active
Paterson, H (ELSEVIER SCIENCE INC, 2011-02)ERK1 and ERK2 (ERK1/2) are central to the regulation of cell division, growth and survival. They are activated by phosphorylation of the Thr- and the Tyr- residues in their Thr-Glu-Tyr activation loops. The dogma is that ... -
Real time fluorescence imaging of PLC gamma translocation and its interaction with the epidermal growth factor receptor
Matsuda, M; Paterson, HF; Rodriguez, R; Fensome, AC; Ellis, MV; et al. (2001-04-30)The translocation of fluorescently tagged PLC gamma and requirements for this process in cells stimulated with EGF were analyzed using real time fluorescence microscopy applied for the first time to monitor growth factor ...