Browsing by author "Vivanco, Maria"
Now showing items 1-4 of 4
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Glucocorticoids inhibit apoptosis during fibrosarcoma development by transcriptionally activating Bcl-x(L)
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2003-05-16)Glucocorticoids influence many physiological processes, and in particular apoptosis, often with opposite effects depending on the cell type examined. We found that during fibrosarcoma development there is a strong increase ... -
Glycogen synthase kinase-3 and Axin function in a β-catenin-independent pathway that regulates neurite outgrowth in neuroblastoma cells
(2003)We have sought to determine the roles of β-catenin and the Wnt signaling pathway in neurite outgrowth using a model cell system, the Neuro-2a neuroblastoma cell line. Activation of the Wnt signaling pathway disrupts a ... -
Loss of P16(INK4a) results in increased glucocorticoid receptor activity during fibrosarcoma development
(NATL ACAD SCIENCES, 2003-03-18)‘Glucocorticoids inhibit proliferation of many cell types, but the relationship between the glucocorticoid receptor (GR) and the proteins regulating cell cycle progression is not fully understood. We previously found that ... -
Nuclear export of α-catenin: overlap between nuclear export signal sequences and the β-catenin binding site
(2004)Mutations in APC or in β-catenin, which are common in colon cancer, lead to constitutive activation of β-catenin/Tcf-dependent signaling. α-Catenin is also found in some colon cancer cell nuclei, and loss of its expression ...
