Browsing by author "Black, Iona"
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Development of chemical tool compounds targeting the non-catalytic functions of tankyrase
Guettler S; Black, I; Guettler, S (Institute of Cancer Research (University Of London), 2023-06-16)Tankyrase (TNKS1 and TNKS2) is a promising target in anti-cancer drug discovery due to its role in regulating cellular processes which are dysregulated in cancer. In addition to catalysing the poly(ADP-ribosyl)ation of ...