Browsing by author "Bhalay, Gurdip"
Now showing items 1-2 of 2
-
Intracellular Metabolomics Identifies Efflux Transporter Inhibitors in a Routine Caco-2 Cell Permeability Assay-Biological Implications.
Naseem, A; Pal, A; Gowan, S; Asad, Y; Donovan, A; et al. (MDPI, 2022-10-19)Caco-2 screens are routinely used in laboratories to measure the permeability of compounds and can identify substrates of efflux transporters. In this study, we hypothesized that efflux transporter inhibition of a compound ... -
Preparation of tyrosine amide derivatives as Rho-kinase inhibitors
Bhalay, G (2018-08-02)The invention relates to compds. of formula I and pharmaceutically acceptable salts and solvates thereof (wherein X1 and X2 are independently CH and N; p = 1 - 3; each R when present is halo; R0 and R1 are independently ...