Browsing by author "Bernauer, Carolina"
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FGF7-FGFR2 autocrine signaling increases growth and chemoresistance of fusion-positive rhabdomyosarcomas.
Milton, CI; Selfe, J; Aladowicz, E; Man, SYK; Bernauer, C; et al. (WILEY, 2021-11-30)Rhabdomyosarcomas are aggressive pediatric soft-tissue sarcomas and include high-risk PAX3-FOXO1 fusion-gene-positive cases. Fibroblast growth factor receptor 4 (FGFR4) is known to contribute to rhabdomyosarcoma progression; ... -
Hypoxia and its therapeutic possibilities in paediatric cancers.
Bernauer, C; Man, YKS; Chisholm, JC; Lepicard, EY; Robinson, SP; et al. (SPRINGERNATURE, 2021-02-02)In tumours, hypoxia-a condition in which the demand for oxygen is higher than its availability-is well known to be associated with reduced sensitivity to radiotherapy and chemotherapy, and with immunosuppression. The ...