Browsing by author "Fernandez Torga, Gonzalo"
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Functional screening reveals HORMAD1-driven gene dependencies associated with translesion synthesis and replication stress tolerance.
Tarantino, D; Walker, C; Weekes, D; Pemberton, H; Davidson, K; et al. (SPRINGERNATURE, 2022-08-05)HORMAD1 expression is usually restricted to germline cells, but it becomes mis-expressed in epithelial cells in ~60% of triple-negative breast cancers (TNBCs), where it is associated with elevated genomic instability (1). ...