Now showing items 1-17 of 17

    • 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population. 

      Takata, R; Takahashi, A; Fujita, M; Momozawa, Y; Saunders, EJ; Yamada, H; Maejima, K; Nakano, K; Nishida, Y; Hishida, A; Matsuo, K; Wakai, K; Yamaji, T; Sawada, N; Iwasaki, M; Tsugane, S; Sasaki, M; Shimizu, A; Tanno, K; Minegishi, N; Suzuki, K; Matsuda, K; Kubo, M; Inazawa, J; Egawa, S; Haiman, CA; Ogawa, O; Obara, W; Kamatani, Y; Akamatsu, S; Nakagawa, H (2019-09-27)
      Genome-wide association studies (GWAS) have identified ~170 genetic loci associated with prostate cancer (PCa) risk, but most of them were identified in European populations. We here performed a GWAS and replication study ...
    • Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. 

      Schumacher, FR; Al Olama, AA; Berndt, SI; Benlloch, S; Ahmed, M; Saunders, EJ; Dadaev, T; Leongamornlert, D; Anokian, E; Cieza-Borrella, C; Goh, C; Brook, MN; Sheng, X; Fachal, L; Dennis, J; Tyrer, J; Muir, K; Lophatananon, A; Stevens, VL; Gapstur, SM; Carter, BD; Tangen, CM; Goodman, PJ; Thompson, IM; Batra, J; Chambers, S; Moya, L; Clements, J; Horvath, L; Tilley, W; Risbridger, GP; Gronberg, H; Aly, M; Nordström, T; Pharoah, P; Pashayan, N; Schleutker, J; Tammela, TLJ; Sipeky, C; Auvinen, A; Albanes, D; Weinstein, S; Wolk, A; Håkansson, N; West, CML; Dunning, AM; Burnet, N; Mucci, LA; Giovannucci, E; Andriole, GL; Cussenot, O; Cancel-Tassin, G; Koutros, S; Beane Freeman, LE; Sorensen, KD; Orntoft, TF; Borre, M; Maehle, L; Grindedal, EM; Neal, DE; Donovan, JL; Hamdy, FC; Martin, RM; Travis, RC; Key, TJ; Hamilton, RJ; Fleshner, NE; Finelli, A; Ingles, SA; Stern, MC; Rosenstein, BS; Kerns, SL; Ostrer, H; Lu, Y-J; Zhang, H-W; Feng, N; Mao, X; Guo, X; Wang, G; Sun, Z; Giles, GG; Southey, MC; MacInnis, RJ; FitzGerald, LM; Kibel, AS; Drake, BF; Vega, A; Gómez-Caamaño, A; Szulkin, R; Eklund, M; Kogevinas, M; Llorca, J; Castaño-Vinyals, G; Penney, KL; Stampfer, M; Park, JY; Sellers, TA; Lin, H-Y; Stanford, JL; Cybulski, C; Wokolorczyk, D; Lubinski, J; Ostrander, EA; Geybels, MS; Nordestgaard, BG; Nielsen, SF; Weischer, M; Bisbjerg, R; Røder, MA; Iversen, P; Brenner, H; Cuk, K; Holleczek, B; Maier, C; Luedeke, M; Schnoeller, T; Kim, J; Logothetis, CJ; John, EM; Teixeira, MR; Paulo, P; Cardoso, M; Neuhausen, SL; Steele, L; Ding, YC; De Ruyck, K; De Meerleer, G; Ost, P; Razack, A; Lim, J; Teo, S-H; Lin, DW; Newcomb, LF; Lessel, D; Gamulin, M; Kulis, T; Kaneva, R; Usmani, N; Singhal, S; Slavov, C; Mitev, V; Parliament, M; Claessens, F; Joniau, S; Van den Broeck, T; Larkin, S; Townsend, PA; Aukim-Hastie, C; Gago-Dominguez, M; Castelao, JE; Martinez, ME; Roobol, MJ; Jenster, G; van Schaik, RHN; Menegaux, F; Truong, T; Koudou, YA; Xu, J; Khaw, K-T; Cannon-Albright, L; Pandha, H; Michael, A; Thibodeau, SN; McDonnell, SK; Schaid, DJ; Lindstrom, S; Turman, C; Ma, J; Hunter, DJ; Riboli, E; Siddiq, A; Canzian, F; Kolonel, LN; Le Marchand, L; Hoover, RN; Machiela, MJ; Cui, Z; Kraft, P; Amos, CI; Conti, DV; Easton, DF; Wiklund, F; Chanock, SJ; Henderson, BE; Kote-Jarai, Z; Haiman, CA; Eeles, RA; Profile Study; Australian Prostate Cancer BioResource (APCB); IMPACT Study; Canary PASS Investigators; Breast and Prostate Cancer Cohort Consortium (BPC3); PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium; Cancer of the Prostate in Sweden (CAPS); Prostate Cancer Genome-wide Association Study of Uncommon Susceptibility Loci (PEGASUS); Genetic Associations and Mechanisms in Oncology (GAME-ON)/Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE) Consortium (2018-07)
      Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data from a custom high-density array of 46,939 ...
    • Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation. 

      Gusev, A; Shi, H; Kichaev, G; Pomerantz, M; Li, F; Long, HW; Ingles, SA; Kittles, RA; Strom, SS; Rybicki, BA; Nemesure, B; Isaacs, WB; Zheng, W; Pettaway, CA; Yeboah, ED; Tettey, Y; Biritwum, RB; Adjei, AA; Tay, E; Truelove, A; Niwa, S; Chokkalingam, AP; John, EM; Murphy, AB; Signorello, LB; Carpten, J; Leske, MC; Wu, S-Y; Hennis, AJM; Neslund-Dudas, C; Hsing, AW; Chu, L; Goodman, PJ; Klein, EA; Witte, JS; Casey, G; Kaggwa, S; Cook, MB; Stram, DO; Blot, WJ; Eeles, RA; Easton, D; Kote-Jarai, Z; Al Olama, AA; Benlloch, S; Muir, K; Giles, GG; Southey, MC; Fitzgerald, LM; Gronberg, H; Wiklund, F; Aly, M; Henderson, BE; Schleutker, J; Wahlfors, T; Tammela, TLJ; Nordestgaard, BG; Key, TJ; Travis, RC; Neal, DE; Donovan, JL; Hamdy, FC; Pharoah, P; Pashayan, N; Khaw, K-T; Stanford, JL; Thibodeau, SN; McDonnell, SK; Schaid, DJ; Maier, C; Vogel, W; Luedeke, M; Herkommer, K; Kibel, AS; Cybulski, C; Wokolorczyk, D; Kluzniak, W; Cannon-Albright, L; Teerlink, C; Brenner, H; Dieffenbach, AK; Arndt, V; Park, JY; Sellers, TA; Lin, H-Y; Slavov, C; Kaneva, R; Mitev, V; Batra, J; Spurdle, A; Clements, JA; Teixeira, MR; Pandha, H; Michael, A; Paulo, P; Maia, S; Kierzek, A; PRACTICAL consortium; Conti, DV; Albanes, D; Berg, C; Berndt, SI; Campa, D; Crawford, ED; Diver, WR; Gapstur, SM; Gaziano, JM; Giovannucci, E; Hoover, R; Hunter, DJ; Johansson, M; Kraft, P; Le Marchand, L; Lindström, S; Navarro, C; Overvad, K; Riboli, E; Siddiq, A; Stevens, VL; Trichopoulos, D; Vineis, P; Yeager, M; Trynka, G; Raychaudhuri, S; Schumacher, FR; Price, AL; Freedman, ML; Haiman, CA; Pasaniuc, B (2016-04-07)
      Although genome-wide association studies have identified over 100 risk loci that explain ∼33% of familial risk for prostate cancer (PrCa), their functional effects on risk remain largely unknown. Here we use genotype data ...
    • Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants. 

      Dadaev, T; Saunders, EJ; Newcombe, PJ; Anokian, E; Leongamornlert, DA; Brook, MN; Cieza-Borrella, C; Mijuskovic, M; Wakerell, S; Olama, AAA; Schumacher, FR; Berndt, SI; Benlloch, S; Ahmed, M; Goh, C; Sheng, X; Zhang, Z; Muir, K; Govindasami, K; Lophatananon, A; Stevens, VL; Gapstur, SM; Carter, BD; Tangen, CM; Goodman, P; Thompson, IM; Batra, J; Chambers, S; Moya, L; Clements, J; Horvath, L; Tilley, W; Risbridger, G; Gronberg, H; Aly, M; Nordström, T; Pharoah, P; Pashayan, N; Schleutker, J; Tammela, TLJ; Sipeky, C; Auvinen, A; Albanes, D; Weinstein, S; Wolk, A; Hakansson, N; West, C; Dunning, AM; Burnet, N; Mucci, L; Giovannucci, E; Andriole, G; Cussenot, O; Cancel-Tassin, G; Koutros, S; Freeman, LEB; Sorensen, KD; Orntoft, TF; Borre, M; Maehle, L; Grindedal, EM; Neal, DE; Donovan, JL; Hamdy, FC; Martin, RM; Travis, RC; Key, TJ; Hamilton, RJ; Fleshner, NE; Finelli, A; Ingles, SA; Stern, MC; Rosenstein, B; Kerns, S; Ostrer, H; Lu, Y-J; Zhang, H-W; Feng, N; Mao, X; Guo, X; Wang, G; Sun, Z; Giles, GG; Southey, MC; MacInnis, RJ; FitzGerald, LM; Kibel, AS; Drake, BF; Vega, A; Gómez-Caamaño, A; Fachal, L; Szulkin, R; Eklund, M; Kogevinas, M; Llorca, J; Castaño-Vinyals, G; Penney, KL; Stampfer, M; Park, JY; Sellers, TA; Lin, H-Y; Stanford, JL; Cybulski, C; Wokolorczyk, D; Lubinski, J; Ostrander, EA; Geybels, MS; Nordestgaard, BG; Nielsen, SF; Weisher, M; Bisbjerg, R; Røder, MA; Iversen, P; Brenner, H; Cuk, K; Holleczek, B; Maier, C; Luedeke, M; Schnoeller, T; Kim, J; Logothetis, CJ; John, EM; Teixeira, MR; Paulo, P; Cardoso, M; Neuhausen, SL; Steele, L; Ding, YC; De Ruyck, K; De Meerleer, G; Ost, P; Razack, A; Lim, J; Teo, S-H; Lin, DW; Newcomb, LF; Lessel, D; Gamulin, M; Kulis, T; Kaneva, R; Usmani, N; Slavov, C; Mitev, V; Parliament, M; Singhal, S; Claessens, F; Joniau, S; Van den Broeck, T; Larkin, S; Townsend, PA; Aukim-Hastie, C; Gago-Dominguez, M; Castelao, JE; Martinez, ME; Roobol, MJ; Jenster, G; van Schaik, RHN; Menegaux, F; Truong, T; Koudou, YA; Xu, J; Khaw, K-T; Cannon-Albright, L; Pandha, H; Michael, A; Kierzek, A; Thibodeau, SN; McDonnell, SK; Schaid, DJ; Lindstrom, S; Turman, C; Ma, J; Hunter, DJ; Riboli, E; Siddiq, A; Canzian, F; Kolonel, LN; Le Marchand, L; Hoover, RN; Machiela, MJ; Kraft, P; PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium; Freedman, M; Wiklund, F; Chanock, S; Henderson, BE; Easton, DF; Haiman, CA; Eeles, RA; Conti, DV; Kote-Jarai, Z (2018-06-11)
      Prostate cancer is a polygenic disease with a large heritable component. A number of common, low-penetrance prostate cancer risk loci have been identified through GWAS. Here we apply the Bayesian multivariate variable ...
    • Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array. 

      Saunders, EJ; Dadaev, T; Leongamornlert, DA; Al Olama, AA; Benlloch, S; Giles, GG; Wiklund, F; Gronberg, H; Haiman, CA; Schleutker, J; Nordestgaard, BG; Travis, RC; Neal, D; Pasayan, N; Khaw, K-T; Stanford, JL; Blot, WJ; Thibodeau, SN; Maier, C; Kibel, AS; Cybulski, C; Cannon-Albright, L; Brenner, H; Park, JY; Kaneva, R; Batra, J; Teixeira, MR; Pandha, H; Govindasami, K; Muir, K; UK Genetic Prostate Cancer Study Collaborators; UK ProtecT Study Collaborators; PRACTICAL Consortium; Easton, DF; Eeles, RA; Kote-Jarai, Z (2016-04)
      Background Germline mutations within DNA-repair genes are implicated in susceptibility to multiple forms of cancer. For prostate cancer (PrCa), rare mutations in BRCA2 and BRCA1 give rise to moderately elevated risk, whereas ...
    • Germline DNA Repair Gene Mutations in Young-onset Prostate Cancer Cases in the UK: Evidence for a More Extensive Genetic Panel. 

      Leongamornlert, DA; Saunders, EJ; Wakerell, S; Whitmore, I; Dadaev, T; Cieza-Borrella, C; Benafif, S; Brook, MN; Donovan, JL; Hamdy, FC; Neal, DE; Muir, K; Govindasami, K; Conti, DV; Kote-Jarai, Z; Eeles, RA (2019-09)
      Background Rare germline mutations in DNA repair genes are associated with prostate cancer (PCa) predisposition and prognosis.Objective To quantify the frequency of germline DNA repair gene mutations in UK PCa cases and ...
    • Germline genetic variation in prostate susceptibility does not predict outcomes in the chemoprevention trials PCPT and SELECT. 

      Ahmed, M; Goh, C; Saunders, E; Cieza-Borrella, C; PRACTICAL consortium; Kote-Jarai, Z; Schumacher, FR; Eeles, R (2020-06)
      Background The development of prostate cancer can be influenced by genetic and environmental factors. Numerous germline SNPs influence prostate cancer susceptibility. The functional pathways in which these SNPs increase ...
    • Germline sequencing DNA repair genes in 5,545 men with aggressive and non-aggressive prostate cancer. 

      Darst, BF; Dadaev, T; Saunders, E; Sheng, X; Wan, P; Pooler, L; Xia, LY; Chanock, S; Berndt, SI; Gapstur, SM; Stevens, V; Albanes, D; Weinstein, SJ; Gnanapragasam, V; Giles, GG; Nguyen-Dumont, T; Milne, RL; Pomerantz, M; Schmidt, JA; Mucci, L; Catalona, WJ; Hetrick, KN; Doheny, KF; MacInnis, RJ; Southey, MC; Eeles, RA; Wiklund, F; Kote-Jarai, Z; Conti, DV; Haiman, CA (2020-08-27)
      Background There is an urgent need to identify factors specifically associated with aggressive prostate cancer (PCa) risk. We investigated whether rare pathogenic, likely pathogenic, or deleterious (P/LP/D) germline variants ...
    • Germline variation at 8q24 and prostate cancer risk in men of European ancestry. 

      Matejcic, M; Saunders, EJ; Dadaev, T; Brook, MN; Wang, K; Sheng, X; Olama, AAA; Schumacher, FR; Ingles, SA; Govindasami, K; Benlloch, S; Berndt, SI; Albanes, D; Koutros, S; Muir, K; Stevens, VL; Gapstur, SM; Tangen, CM; Batra, J; Clements, J; Gronberg, H; Pashayan, N; Schleutker, J; Wolk, A; West, C; Mucci, L; Kraft, P; Cancel-Tassin, G; Sorensen, KD; Maehle, L; Grindedal, EM; Strom, SS; Neal, DE; Hamdy, FC; Donovan, JL; Travis, RC; Hamilton, RJ; Rosenstein, B; Lu, Y-J; Giles, GG; Kibel, AS; Vega, A; Bensen, JT; Kogevinas, M; Penney, KL; Park, JY; Stanford, JL; Cybulski, C; Nordestgaard, BG; Brenner, H; Maier, C; Kim, J; Teixeira, MR; Neuhausen, SL; De Ruyck, K; Razack, A; Newcomb, LF; Lessel, D; Kaneva, R; Usmani, N; Claessens, F; Townsend, PA; Gago-Dominguez, M; Roobol, MJ; Menegaux, F; Khaw, K-T; Cannon-Albright, LA; Pandha, H; Thibodeau, SN; Schaid, DJ; PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium; Wiklund, F; Chanock, SJ; Easton, DF; Eeles, RA; Kote-Jarai, Z; Conti, DV; Haiman, CA (2018-11-05)
      Chromosome 8q24 is a susceptibility locus for multiple cancers, including prostate cancer. Here we combine genetic data across the 8q24 susceptibility region from 71,535 prostate cancer cases and 52,935 controls of European ...
    • Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium. 

      Lophatananon, A; Stewart-Brown, S; Kote-Jarai, Z; Olama, AAA; Garcia, SB; Neal, DE; Hamdy, FC; Donovan, JL; Giles, GG; Fitzgerald, LM; Southey, MC; Pharoah, P; Pashayan, N; Gronberg, H; Wiklund, F; Aly, M; Stanford, JL; Brenner, H; Dieffenbach, AK; Arndt, V; Park, JY; Lin, H-Y; Sellers, T; Slavov, C; Kaneva, R; Mitev, V; Batra, J; Spurdle, A; Clements, JA; APCB BioResource; PRACTICAL consortium; Easton, D; Eeles, RA; Muir, K (2017-08)
      Background Evidence on height and prostate cancer risk is mixed, however, recent studies with large data sets support a possible role for its association with the risk of aggressive prostate cancer.Methods We analysed data ...
    • Identification of Germline Genetic Variants that Increase Prostate Cancer Risk and Influence Development of Aggressive Disease. 

      Saunders, EJ; Kote-Jarai, Z; Eeles, RA (2021-02-12)
      Prostate cancer (PrCa) is a heterogeneous disease, which presents in individual patients across a diverse phenotypic spectrum ranging from indolent to fatal forms. No robust biomarkers are currently available to enable ...
    • LocusExplorer: a user-friendly tool for integrated visualization of human genetic association data and biological annotations. 

      Dadaev, T; Leongamornlert, DA; Saunders, EJ; Eeles, R; Kote-Jarai, Z (2016-03)
      Unlabelled : In this article, we present LocusExplorer, a data visualization and exploration tool for genetic association data. LocusExplorer is written in R using the Shiny library, providing access to powerful R-based ...
    • Rare Germline Variants in ATM Predispose to Prostate Cancer: A PRACTICAL Consortium Study. 

      Karlsson, Q; Brook, MN; Dadaev, T; Wakerell, S; Saunders, EJ; Muir, K; Neal, DE; Giles, GG; MacInnis, RJ; Thibodeau, SN; McDonnell, SK; Cannon-Albright, L; Teixeira, MR; Paulo, P; Cardoso, M; Huff, C; Li, D; Yao, Y; Scheet, P; Permuth, JB; Stanford, JL; Dai, JY; Ostrander, EA; Cussenot, O; Cancel-Tassin, G; Hoegel, J; Herkommer, K; Schleutker, J; Tammela, TLJ; Rathinakannan, V; Sipeky, C; Wiklund, F; Grönberg, H; Aly, M; Isaacs, WB; Dickinson, JL; FitzGerald, LM; Chua, MLK; Nguyen-Dumont, T; PRACTICAL Consortium; Schaid, DJ; Southey, MC; Eeles, RA; Kote-Jarai, Z (2021-01-09)
      Germline ATM mutations are suggested to contribute to predisposition to prostate cancer (PrCa). Previous studies have had inadequate power to estimate variant effect sizes. To precisely estimate the contribution of germline ...
    • Rare germline variants in DNA repair genes and the angiogenesis pathway predispose prostate cancer patients to develop metastatic disease. 

      Mijuskovic, M; Saunders, EJ; Leongamornlert, DA; Wakerell, S; Whitmore, I; Dadaev, T; Cieza-Borrella, C; Govindasami, K; Brook, MN; Haiman, CA; Conti, DV; Eeles, RA; Kote-Jarai, Z (2018-07)
      Background Prostate cancer (PrCa) demonstrates a heterogeneous clinical presentation ranging from largely indolent to lethal. We sought to identify a signature of rare inherited variants that distinguishes between these ...
    • The BARCODE1 Pilot: a feasibility study of using germline single nucleotide polymorphisms to target prostate cancer screening. 

      Benafif, S; Ni Raghallaigh, H; McGrowder, E; Saunders, EJ; Brook, MN; Saya, S; Rageevakumar, R; Wakerell, S; James, D; Chamberlain, A; Taylor, N; Hogben, M; Benton, B; D'Mello, L; Myhill, K; Mikropoulos, C; Bowen-Perkins, H; Rafi, I; Ferris, M; Beattie, A; Kuganolipava, S; Sevenoaks, T; Bower, J; Kumar, P; Hazell, S; deSouza, NM; Antoniou, A; Bancroft, E; Kote-Jarai, Z; Eeles, R (2021-07-02)
      Objectives To assess the feasibility and uptake of a community-based prostate cancer (PCa) screening programme selecting men according to their genetic risk of PCa. To assess the uptake of PCa screening investigations by ...
    • The PROFILE Feasibility Study: Targeted Screening of Men With a Family History of Prostate Cancer. 

      Castro, E; Mikropoulos, C; Bancroft, EK; Dadaev, T; Goh, C; Taylor, N; Saunders, E; Borley, N; Keating, D; Page, EC; Saya, S; Hazell, S; Livni, N; deSouza, N; Neal, D; Hamdy, FC; Kumar, P; Antoniou, AC; Kote-Jarai, Z; PROFILE Study Steering Committee; Eeles, RA (2016-06)
      Background A better assessment of individualized prostate cancer (PrCa) risk is needed to improve screening. The use of the prostate-specific antigen (PSA) level for screening in the general population has limitations and ...
    • Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. 

      Conti, DV; Darst, BF; Moss, LC; Saunders, EJ; Sheng, X; Chou, A; Schumacher, FR; Olama, AAA; Benlloch, S; Dadaev, T; Brook, MN; Sahimi, A; Hoffmann, TJ; Takahashi, A; Matsuda, K; Momozawa, Y; Fujita, M; Muir, K; Lophatananon, A; Wan, P; Le Marchand, L; Wilkens, LR; Stevens, VL; Gapstur, SM; Carter, BD; Schleutker, J; Tammela, TLJ; Sipeky, C; Auvinen, A; Giles, GG; Southey, MC; MacInnis, RJ; Cybulski, C; Wokołorczyk, D; Lubiński, J; Neal, DE; Donovan, JL; Hamdy, FC; Martin, RM; Nordestgaard, BG; Nielsen, SF; Weischer, M; Bojesen, SE; Røder, MA; Iversen, P; Batra, J; Chambers, S; Moya, L; Horvath, L; Clements, JA; Tilley, W; Risbridger, GP; Gronberg, H; Aly, M; Szulkin, R; Eklund, M; Nordström, T; Pashayan, N; Dunning, AM; Ghoussaini, M; Travis, RC; Key, TJ; Riboli, E; Park, JY; Sellers, TA; Lin, H-Y; Albanes, D; Weinstein, SJ; Mucci, LA; Giovannucci, E; Lindstrom, S; Kraft, P; Hunter, DJ; Penney, KL; Turman, C; Tangen, CM; Goodman, PJ; Thompson, IM; Hamilton, RJ; Fleshner, NE; Finelli, A; Parent, M-É; Stanford, JL; Ostrander, EA; Geybels, MS; Koutros, S; Freeman, LEB; Stampfer, M; Wolk, A; Håkansson, N; Andriole, GL; Hoover, RN; Machiela, MJ; Sørensen, KD; Borre, M; Blot, WJ; Zheng, W; Yeboah, ED; Mensah, JE; Lu, Y-J; Zhang, H-W; Feng, N; Mao, X; Wu, Y; Zhao, S-C; Sun, Z; Thibodeau, SN; McDonnell, SK; Schaid, DJ; West, CML; Burnet, N; Barnett, G; Maier, C; Schnoeller, T; Luedeke, M; Kibel, AS; Drake, BF; Cussenot, O; Cancel-Tassin, G; Menegaux, F; Truong, T; Koudou, YA; John, EM; Grindedal, EM; Maehle, L; Khaw, K-T; Ingles, SA; Stern, MC; Vega, A; Gómez-Caamaño, A; Fachal, L; Rosenstein, BS; Kerns, SL; Ostrer, H; Teixeira, MR; Paulo, P; Brandão, A; Watya, S; Lubwama, A; Bensen, JT; Fontham, ETH; Mohler, J; Taylor, JA; Kogevinas, M; Llorca, J; Castaño-Vinyals, G; Cannon-Albright, L; Teerlink, CC; Huff, CD; Strom, SS; Multigner, L; Blanchet, P; Brureau, L; Kaneva, R; Slavov, C; Mitev, V; Leach, RJ; Weaver, B; Brenner, H; Cuk, K; Holleczek, B; Saum, K-U; Klein, EA; Hsing, AW; Kittles, RA; Murphy, AB; Logothetis, CJ; Kim, J; Neuhausen, SL; Steele, L; Ding, YC; Isaacs, WB; Nemesure, B; Hennis, AJM; Carpten, J; Pandha, H; Michael, A; De Ruyck, K; De Meerleer, G; Ost, P; Xu, J; Razack, A; Lim, J; Teo, S-H; Newcomb, LF; Lin, DW; Fowke, JH; Neslund-Dudas, C; Rybicki, BA; Gamulin, M; Lessel, D; Kulis, T; Usmani, N; Singhal, S; Parliament, M; Claessens, F; Joniau, S; Van den Broeck, T; Gago-Dominguez, M; Castelao, JE; Martinez, ME; Larkin, S; Townsend, PA; Aukim-Hastie, C; Bush, WS; Aldrich, MC; Crawford, DC; Srivastava, S; Cullen, JC; Petrovics, G; Casey, G; Roobol, MJ; Jenster, G; van Schaik, RHN; Hu, JJ; Sanderson, M; Varma, R; McKean-Cowdin, R; Torres, M; Mancuso, N; Berndt, SI; Van Den Eeden, SK; Easton, DF; Chanock, SJ; Cook, MB; Wiklund, F; Nakagawa, H; Witte, JS; Eeles, RA; Kote-Jarai, Z; Haiman, CA (2021-01-04)
      Prostate cancer is a highly heritable disease with large disparities in incidence rates across ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer genome-wide association studies (107,247 ...