Now showing items 4187-4188 of 4188

    • αB-crystallin Expression in Breast Cancer is Associated with Brain Metastasis. 

      Voduc, KD; Nielsen, TO; Perou, CM; Harrell, JC; Fan, C; Kennecke, H; Minn, AJ; Cryns, VL; Cheang, MCU (2015-10)
      <h4>Background/objectives</h4>The molecular chaperone αB-crystallin is expressed in estrogen receptor, progesterone receptor and human epidermal growth factor receptor-2 "triple-negative" breast carcinomas and promotes ...
    • β-Catenin signaling is a critical event in ErbB2-mediated mammary tumor progression. 

      Schade, B; Lesurf, R; Sanguin-Gendreau, V; Bui, T; Deblois, G; O'Toole, SA; Millar, EKA; Zardawi, SJ; Lopez-Knowles, E; Sutherland, RL; Giguère, V; Kahn, M; Hallett, M; Muller, WJ (2013-07)
      Although ERBB2 amplification and overexpression is correlated with poor outcome in breast cancer, the molecular mechanisms underlying the aggressive nature of these tumors has not been fully elucidated. To investigate this ...