Browsing by author "Kirby, Anna"
Now showing items 1-15 of 15
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3-Dimensional objective aesthetic evaluation to replace panel assessment after breast-conserving treatment.
Godden, AR; O'Connell, RL; Barry, PA; Krupa, KCD; Wolf, LM; et al. (2020-11)Background Two-thirds of patients with early breast cancer undergo breast-conserving treatment (BCT). Aesthetic outcome is important and has long term implications for psychosocial wellbeing. The aesthetic goal of BCT is ... -
Adaptive radiotherapy for breast cancer.
De-Colle, C; Kirby, A; Russell, N; Shaitelman, SF; Currey, A; et al. (Elsevier BV, 2023-03-01)Research in the field of local and locoregional breast cancer radiotherapy aims to maintain excellent oncological outcomes while reducing treatment-related toxicity. Adaptive radiotherapy (ART) considers variations in ... -
Can patient decision aids reduce decisional conflict in a de-escalation of breast radiotherapy clinical trial? The PRIMETIME Study Within a Trial implemented using a cluster stepped-wedge trial design.
Bhattacharya, IS; Haviland, JS; Turner, L; Stobart, H; Balasopoulou, A; et al. (2021-06-14)<h4>Background</h4>For patients with early breast cancer considered at very-low risk of local relapse, risks of radiotherapy may outweigh the benefits. Decisions regarding treatment omission can lead to patient uncertainty ... -
Comparison of Immediate versus Delayed DIEP Flap Reconstruction in Women Who Require Postmastectomy Radiotherapy.
O'Connell, RL; Di Micco, R; Khabra, K; Kirby, AM; Harris, PA; et al. (2018-09)Background The authors investigated aesthetic outcome and patient satisfaction in women who have undergone deep inferior epigastric artery perforator (DIEP) flap reconstruction in the setting of postmastectomy radiotherapy. ... -
European radiation oncology after one year of COVID-19 pandemic.
Slotman, BJ; Cremades, V; Kirby, AM; Ricardi, U -
European Society of Cardiology quality indicators for the prevention and management of cancer therapy-related cardiovascular toxicity in cancer treatment.
Lee, GA; Aktaa, S; Baker, E; Gale, CP; Yaseen, IF; et al. (Oxford University Press (OUP), 2022-12-13)AIMS: To develop quality indicators (QIs) for the evaluation of the prevention and management of cancer therapy-related cardiovascular toxicity. METHODS AND RESULTS: We followed the European Society of Cardiology (ESC) ... -
Hypofractionated breast radiotherapy for 1 week versus 3 weeks (FAST-Forward): 5-year efficacy and late normal tissue effects results from a multicentre, non-inferiority, randomised, phase 3 trial
Haviland, J; Sydenham, M; Hopwood, P; Kirby, A; Somaiah, N; et al. -
Looking Back: International Practice Patterns in Breast Radiation Oncology From a Case-Based Survey Across 54 Countries During the First Surge of the COVID-19 Pandemic.
Oladeru, OT; Dunn, SA; Li, J; Coles, CE; Yamauchi, C; et al. (LIPPINCOTT WILLIAMS & WILKINS, 2023-07-01)PURPOSE: The COVID-19 pandemic has profoundly affected cancer care worldwide, including radiation therapy (RT) for breast cancer (BC), because of risk-based resource allocation. We report the evolution of international ... -
Mean heart dose variation over a course of breath-holding breast cancer radiotherapy.
Dunkerley, N; Bartlett, FR; Kirby, AM; Evans, PM; Donovan, EM (2016-11)Objective The purpose of the work was to estimate the dose received by the heart throughout a course of breath-holding breast radiotherapy.Methods 113 cone-beam CT (CBCT) scans were acquired for 20 patients treated within ... -
Patient-Reported Outcomes Over 5 Years After Whole- or Partial-Breast Radiotherapy: Longitudinal Analysis of the IMPORT LOW (CRUK/06/003) Phase III Randomized Controlled Trial.
Bhattacharya, IS; Haviland, JS; Kirby, AM; Kirwan, CC; Hopwood, P; et al. (2019-02)Purpose IMPORT LOW demonstrated noninferiority of partial-breast and reduced-dose radiotherapy versus whole-breast radiotherapy for local relapse and similar or reduced toxicity at 5 years. Comprehensive patient-reported ... -
Pre-operative Radiotherapy And Deep Inferior Epigastric Artery Perforator (DIEP) flAp study (PRADA): Aesthetic outcome and patient satisfaction at one year.
Godden, AR; Micha, A; O'Connell, RL; Mohammed, K; Kirby, AM; et al. (ELSEVIER SCI LTD, 2023-03-01)INTRODUCTION: The optimal combination of radiotherapy and breast reconstruction has not yet been defined. Post-mastectomy radiotherapy (PMRT) has deleterious effects on breast reconstruction, leading to caution amongst ... -
Proton Beam Therapy for Early Breast Cancer: A Systematic Review and Meta-analysis of Clinical Outcomes.
Holt, F; Probert, J; Darby, SC; Haviland, JS; Coles, CE; et al. (ELSEVIER SCIENCE INC, 2023-11-15)PURPOSE: Adjuvant proton beam therapy (PBT) is increasingly available to patients with breast cancer. It achieves better planned dose distributions than standard photon radiation therapy and therefore may reduce the risks. ... -
The role of the radiation therapy breast boost in the 2020s.
Dzhugashvili, M; Veldeman, L; Kirby, AM (CHURCHILL LIVINGSTONE, 2023-03-17)Given that most local relapses of breast cancer occur proximal to the original location of the primary, the delivery of additional radiation dose to breast tissue that contained the original primary cancer (known as a ... -
Selection criteria for early breast cancer patients in the DBCG proton trial - The randomised phase III trial strategy.
Stick, LB; Lorenzen, EL; Yates, ES; Anandadas, C; Andersen, K; et al.Background and purpose Adjuvant radiotherapy of internal mammary nodes (IMN) improves survival in high-risk early breast cancer patients but inevitably leads to more dose to heart and lung. Target coverage is often compromised ... -
Three-dimensional simulation of aesthetic outcome from breast-conserving surgery compared with viewing photographs or standard care: randomized clinical trial.
Godden, AR; Micha, A; Wolf, LM; Pitches, C; Barry, PA; et al. (OXFORD UNIV PRESS, 2021-10-23)INTRODUCTION: Over half of women with surgically managed breast cancer in the UK undergo breast-conserving treatment (BCT). While photographs are shown prior to reconstructive surgery or complex oncoplastic procedures, ...