Browsing by author "Harris, Emma"
Now showing items 1-20 of 22
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A Dosimetric Comparison of Breast Radiotherapy Techniques to Treat Locoregional Lymph Nodes Including the Internal Mammary Chain.
Ranger, A; Dunlop, A; Hutchinson, K; Convery, H; Maclennan, MK; et al. (ELSEVIER SCIENCE LONDON, 2018-06-01)AIMS: Radiotherapy target volumes in early breast cancer treatment increasingly include the internal mammary chain (IMC). In order to maximise survival benefits of IMC radiotherapy, doses to the heart and lung should be ... -
A multicentre study of the evidence for customized margins in photon breast boost radiotherapy.
Harris, EJ; Mukesh, MB; Donovan, EM; Kirby, AM; Haviland, JS; et al. (BRITISH INST RADIOLOGY, 2016-01-01)OBJECTIVE: To determine if subsets of patients may benefit from smaller or larger margins when using laser setup and bony anatomy verification of breast tumour bed (TB) boost radiotherapy (RT). METHODS: Verification imaging ... -
Amplitude based segmentation of ultrasound echoes for attenuation coefficient estimation.
Civale, J; Bamber, J; Harris, E (ELSEVIER, 2021-03-01)In vivo ultrasound attenuation coefficient measurements are of interest as they can provide insight into tissue pathology. They are also needed so that measurements of the tissue's frequency dependent ultrasound backscattering ... -
Classification of fibroglandular tissue distribution in the breast based on radiotherapy planning CT.
Juneja, P; Evans, P; Windridge, D; Harris, E (BIOMED CENTRAL LTD, 2016-01-14)BACKGROUND: Accurate segmentation of breast tissues is required for a number of applications such as model based deformable registration in breast radiotherapy. The accuracy of breast tissue segmentation is affected by the ... -
Combined Ultrasound and Cone Beam CT Improves Target Segmentation for Image Guided Radiation Therapy in Uterine Cervix Cancer.
Mason, SA; White, IM; O'Shea, T; McNair, HA; Alexander, S; et al. (ELSEVIER SCIENCE INC, 2019-07-01)PURPOSE: Adaptive radiation therapy strategies could account for interfractional uterine motion observed in patients with cervix cancer, but the current cone beam computed tomography (CBCT)-based treatment workflow is ... -
Development of 3D extended-aperture spatial compounding to improve ultrasound-based localization of the uterus for radiotherapy treatment
Mason, SA; White, IM; O'Shea, TP; Lalondrelle, S; Bamber, JC; et al. (IEEE, 2019-02-25) -
Does breast composition influence late adverse effects in breast radiotherapy?
Juneja, P; Bonora, M; Haviland, JS; Harris, E; Evans, P; et al. (CHURCHILL LIVINGSTONE, 2016-04-01)BACKGROUND: Large breast size is associated with increased risk of late adverse effects after surgery and radiotherapy for early breast cancer. It is hypothesised that effects of radiotherapy on adipose tissue are responsible ... -
Dynamic contrast enhanced ultrasound imaging; the effect of imaging modes and parameter settings for a microvascular phantom
Moghimirad, E; Bamber, J; Harris, E (IEEE, 2018-01-01) -
First evaluation of the feasibility of MLC tracking using ultrasound motion estimation.
Fast, MF; O'Shea, TP; Nill, S; Oelfke, U; Harris, EJ (WILEY, 2016-08-01)PURPOSE: To quantify the performance of the Clarity ultrasound (US) imaging system (Elekta AB, Stockholm, Sweden) for real-time dynamic multileaf collimator (MLC) tracking. METHODS: The Clarity calibration and quality ... -
High frequency ultrasound vibrational shear wave elastography for preclinical research.
Civale, J; Parasaram, V; Bamber, JC; Harris, EJ (IOP Publishing Ltd, 2022-12-07)Preclinical evaluation of novel therapies using models of cancer is an important tool in cancer research, where imaging can provide non-invasive tools to characterise the internal structure and function of tumours. The ... -
Improving 3D ultrasound prostate localisation in radiotherapy through increased automation of interfraction matching.
Grimwood, A; Rivaz, H; Zhou, H; McNair, HA; Jakubowski, K; et al. (ELSEVIER IRELAND LTD, 2020-08-01)BACKGROUND AND PURPOSE: Daily image guidance is standard care for prostate radiotherapy. Innovations which improve the accuracy and efficiency of ultrasound guidance are needed, particularly with respect to reducing ... -
In Vivo Validation of Elekta's Clarity Autoscan for Ultrasound-based Intrafraction Motion Estimation of the Prostate During Radiation Therapy.
Grimwood, A; McNair, HA; O'Shea, TP; Gilroy, S; Thomas, K; et al. (ELSEVIER SCIENCE INC, 2018-11-15)PURPOSE: Our purpose was to perform an in vivo validation of ultrasound imaging for intrafraction motion estimation using the Elekta Clarity Autoscan system during prostate radiation therapy. The study was conducted as ... -
Is breast seroma after tumour resection associated with patient-reported breast appearance change following radiotherapy? Results from the IMPORT HIGH (CRUK/06/003) trial.
Bhattacharya, IS; Haviland, JS; Perotti, C; Eaton, D; Gulliford, S; et al. (ELSEVIER IRELAND LTD, 2019-07)BACKGROUND: Seroma describes a collection of serous fluid within a cavity, occurring following surgery. Seroma is associated with normal tissue effects (NTE) following breast radiotherapy, as reported by clinicians and on ... -
Magnitude of observer error using cone beam CT for prostate interfraction motion estimation: effect of reducing scan length or increasing exposure.
McNair, HA; Harris, EJ; Hansen, VN; Thomas, K; South, C; et al. (BRITISH INST RADIOLOGY, 2015-10-01)OBJECTIVE: Cone beam CT (CBCT) enables soft-tissue registration to planning CT for position verification in radiotherapy. The aim of this study was to determine the interobserver error (IOE) in prostate position verification ... -
Plane wave versus focused transmissions for contrast enhanced ultrasound imaging: the role of parameter settings and the effects of flow rate on contrast measurements.
Moghimirad, E; Bamber, J; Harris, E (IOP PUBLISHING LTD, 2019-04-23)Contrast enhanced ultrasound (CEUS) and dynamic contrast enhanced ultrasound (DCE-US) can be used to provide information about the vasculature aiding diagnosis and monitoring of a number of pathologies including cancer. ... -
Preclinical Three-Dimensional Vibrational Shear Wave Elastography for Mapping of Tumour Biomechanical Properties In Vivo.
Parasaram, V; Civale, J; Bamber, JC; Robinson, SP; Jamin, Y; et al. (MDPI, 2022-10-03)Preclinical investigation of the biomechanical properties of tissues and their treatment-induced changes are essential to support drug-discovery, clinical translation of biomarkers of treatment response, and studies of ... -
Prediction of pelvic tumour coverage by magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) from referral imaging.
Lam, NFD; Rivens, I; Giles, SL; Harris, E; deSouza, NM; et al. (TAYLOR & FRANCIS LTD, 2020-01-01)BACKGROUND: Patient suitability for magnetic resonance-guided high intensity focused ultrasound (MRgHIFU) ablation of pelvic tumors is initially evaluated clinically for treatment feasibility using referral images, acquired ... -
Real-time intrafraction motion monitoring in external beam radiotherapy.
Bertholet, J; Knopf, A; Eiben, B; McClelland, J; Grimwood, A; et al. (IOP PUBLISHING LTD, 2019-08-07)Radiotherapy (RT) aims to deliver a spatially conformal dose of radiation to tumours while maximizing the dose sparing to healthy tissues. However, the internal patient anatomy is constantly moving due to respiratory, ... -
Review of ultrasound image guidance in external beam radiotherapy part II: intra-fraction motion management and novel applications.
O'Shea, T; Bamber, J; Fontanarosa, D; van der Meer, S; Verhaegen, F; et al. (IOP PUBLISHING LTD, 2016-04-21)Imaging has become an essential tool in modern radiotherapy (RT), being used to plan dose delivery prior to treatment and verify target position before and during treatment. Ultrasound (US) imaging is cost-effective in ... -
Temporal regularization of ultrasound-based liver motion estimation for image-guided radiation therapy.
O'Shea, TP; Bamber, JC; Harris, EJ (WILEY, 2016-01-01)PURPOSE: Ultrasound-based motion estimation is an expanding subfield of image-guided radiation therapy. Although ultrasound can detect tissue motion that is a fraction of a millimeter, its accuracy is variable. For controlling ...