Browsing by author "Desouza, Nandita"
Now showing items 41-60 of 65
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Prediction of pelvic tumour coverage by magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) from referral imaging.
Lam, NFD; Rivens, I; Giles, SL; Harris, E; deSouza, NM; et al. (TAYLOR & FRANCIS LTD, 2020-01-01)BACKGROUND: Patient suitability for magnetic resonance-guided high intensity focused ultrasound (MRgHIFU) ablation of pelvic tumors is initially evaluated clinically for treatment feasibility using referral images, acquired ... -
Preoperative imaging in patients undergoing trachelectomy for cervical cancer: validation of a combined T2- and diffusion-weighted endovaginal MRI technique at 3.0 T.
Downey, K; Shepherd, JH; Attygalle, AD; Hazell, S; Morgan, VA; et al. (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2014-05-01)AIM: The aim of this study is to validate high-resolution endovaginal T2- and diffusion-weighted MRI measurements (tumour size, volume and length of uninvolved cervical canal) against histology in patients undergoing ... -
Radiomic features of cervical cancer on T2-and diffusion-weighted MRI: Prognostic value in low-volume tumors suitable for trachelectomy.
Wormald, BW; Doran, SJ; Ind, TE; D'Arcy, J; Petts, J; et al. (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2020-01-01)BACKGROUND: Textural features extracted from MRI potentially provide prognostic information additional to volume for influencing surgical management of cervical cancer. PURPOSE: To identify textural features that differ ... -
Separation of type and grade in cervical tumours using non-mono-exponential models of diffusion-weighted MRI.
Winfield, JM; Orton, MR; Collins, DJ; Ind, TEJ; Attygalle, A; et al. (SPRINGER, 2017-02-01)OBJECTIVES: Assessment of empirical diffusion-weighted MRI (DW-MRI) models in cervical tumours to investigate whether fitted parameters distinguish between types and grades of tumours. METHODS: Forty-two patients (24 ... -
Spect perfusion imaging versus CT for predicting radiation injury to normal lung in lung cancer patients.
Weller, A; Dunlop, A; Oxer, A; Gunapala, R; Murray, I; et al. (BRITISH INST RADIOLOGY, 2019-09-01)OBJECTIVES: In non-small cell lung cancer (NSCLC) patients, to establish whether the fractional volumes of irradiated anatomic or perfused lung differed between those with and without deteriorating lung function or radiation ... -
Stability of radiomics features in apparent diffusion coefficient maps from a multi-centre test-retest trial.
Peerlings, J; Woodruff, HC; Winfield, JM; Ibrahim, A; Van Beers, BE; et al. (NATURE PORTFOLIO, 2019-03-18)Quantitative radiomics features, extracted from medical images, characterize tumour-phenotypes and have been shown to provide prognostic value in predicting clinical outcomes. Stability of radiomics features extracted from ... -
Standard and Hypofractionated Dose Escalation to Intraprostatic Tumor Nodules in Localized Prostate Cancer: Efficacy and Toxicity in the DELINEATE Trial.
Murray, JR; Tree, AC; Alexander, EJ; Sohaib, A; Hazell, S; et al. (ELSEVIER SCIENCE INC, 2020-03-15)PURPOSE: To report a planned analysis of the efficacy and toxicity of dose escalation to the intraprostatic dominant nodule identified on multiparametric magnetic resonance imaging using standard and hypofractionated ... -
Standardised lesion segmentation for imaging biomarker quantitation: a consensus recommendation from ESR and EORTC.
deSouza, NM; van der Lugt, A; Deroose, CM; Alberich-Bayarri, A; Bidaut, L; et al. (SPRINGER, 2022-10-04)BACKGROUND: Lesion/tissue segmentation on digital medical images enables biomarker extraction, image-guided therapy delivery, treatment response measurement, and training/validation for developing artificial intelligence ... -
Strategies and technical challenges for imaging oligometastatic disease: Recommendations from the European Organisation for Research and Treatment of Cancer imaging group.
deSouza, NM; Liu, Y; Chiti, A; Oprea-Lager, D; Gebhart, G; et al. (ELSEVIER SCI LTD, 2018-03-01)Patients with oligometastatic disease (OMD) often have controllable symptoms, and cures are possible. Technical improvements in surgery and radiotherapy have introduced the option of metastasis-directed ablative therapies ... -
The BARCODE1 Pilot: a feasibility study of using germline single nucleotide polymorphisms to target prostate cancer screening.
Benafif, S; Ni Raghallaigh, H; McGrowder, E; Saunders, EJ; Brook, MN; et al. (WILEY, 2021-07-02)OBJECTIVES: To assess the feasibility and uptake of a community-based prostate cancer (PCa) screening programme selecting men according to their genetic risk of PCa. To assess the uptake of PCa screening investigations by ... -
The effect of FASN inhibition on the growth and metabolism of a cisplatin-resistant ovarian carcinoma model.
Papaevangelou, E; Almeida, GS; Box, C; deSouza, NM; Chung, Y-L (WILEY, 2018-08-15)Overexpression of fatty acid synthase (FASN), a key regulator of the de novo synthesis of fatty acids, has been demonstrated in a variety of cancers and is associated with poor prognosis and increased multidrug resistance. ... -
The potential role of three-dimensional surface imaging as a tool to evaluate aesthetic outcome after Breast Conserving Therapy (BCT)
O'Connell, RL; Di Micco, R; Khabra, K; Wolf, L; deSouza, N; et al. (2017-07-01) -
The potential role of three-dimensional surface imaging as a tool to evaluate aesthetic outcome after Breast Conserving Therapy (BCT).
O'Connell, RL; Di Micco, R; Khabra, K; Wolf, L; deSouza, N; et al. (WILEY, 2017-04-01)PURPOSE: To establish whether objective measurements of symmetry of volume and shape using three-dimensional surface imaging (3D-SI) can be used as surrogate markers of aesthetic outcome in patients who have undergone ... -
The PROFILE Feasibility Study: Targeted Screening of Men With a Family History of Prostate Cancer.
Castro, E; Mikropoulos, C; Bancroft, EK; Dadaev, T; Goh, C; et al. (WILEY, 2016-06-01)BACKGROUND: A better assessment of individualized prostate cancer (PrCa) risk is needed to improve screening. The use of the prostate-specific antigen (PSA) level for screening in the general population has limitations and ... -
Twenty Years On: RECIST as a Biomarker of Response in Solid Tumours an EORTC Imaging Group - ESOI Joint Paper.
Fournier, L; de Geus-Oei, L-F; Regge, D; Oprea-Lager, D-E; D'Anastasi, M; et al. (FRONTIERS MEDIA SA, 2022-01-10)Response evaluation criteria in solid tumours (RECIST) v1.1 are currently the reference standard for evaluating efficacy of therapies in patients with solid tumours who are included in clinical trials, and they are widely ... -
Utility of Multi-Parametric Quantitative Magnetic Resonance Imaging for Characterization and Radiotherapy Response Assessment in Soft-Tissue Sarcomas and Correlation With Histopathology.
Winfield, JM; Miah, AB; Strauss, D; Thway, K; Collins, DJ; et al. (FRONTIERS MEDIA SA, 2019-04-25)Purpose: To evaluate repeatability of quantitative multi-parametric MRI in retroperitoneal sarcomas, assess parameter changes with radiotherapy, and correlate pre-operative values with histopathological findings in the ... -
Validated imaging biomarkers as decision-making tools in clinical trials and routine practice: current status and recommendations from the EIBALL* subcommittee of the European Society of Radiology (ESR).
deSouza, NM; Achten, E; Alberich-Bayarri, A; Bamberg, F; Boellaard, R; et al. (SPRINGER, 2019-08-29)Observer-driven pattern recognition is the standard for interpretation of medical images. To achieve global parity in interpretation, semi-quantitative scoring systems have been developed based on observer assessments; ... -
Validating a robust double-quantum-filtered (1) H MRS lactate measurement method in high-grade brain tumours.
Payne, GS; Harris, LM; Cairns, GS; Messiou, C; deSouza, NM; et al. (WILEY-BLACKWELL, 2016-10-01)(1) H MRS measurements of lactate are often confounded by overlapping lipid signals. Double-quantum (DQ) filtering eliminates lipid signals and permits single-shot measurements, which avoid subtraction artefacts in moving ... -
Validation of T2- and diffusion-weighted magnetic resonance imaging for mapping intra-prostatic tumour prior to focal boost dose-escalation using intensity-modulated radiotherapy (IMRT).
Alexander, EJ; Murray, JR; Morgan, VA; Giles, SL; Riches, SF; et al. (ELSEVIER IRELAND LTD, 2019-12-01)BACKGROUND AND PURPOSE: To assess the diagnostic accuracy and inter-observer agreement of T2-weighted (T2W) and diffusion-weighted (DW) magnetic resonance imaging (MRI) for mapping intra-prostatic tumour lesions (IPLs) for ... -
Validation of the Vectra XT three-dimensional imaging system for measuring breast volume and symmetry following oncological reconstruction.
O'Connell, RL; Khabra, K; Bamber, JC; deSouza, N; Meybodi, F; et al. (SPRINGER, 2018-09-01)PURPOSE: Three-dimensional surface imaging (3D-SI) of the breasts enables the measurement of breast volume and shape symmetry. If these measurements were sufficiently accurate and repeatable, they could be used in planning ...