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dc.contributor.authorRietveld, MJAen_US
dc.contributor.authorHusson, Oen_US
dc.contributor.authorVos, MCCen_US
dc.contributor.authorvan de Poll-Franse, LVen_US
dc.contributor.authorOttevanger, PBNen_US
dc.contributor.authorEzendam, NPMen_US
dc.coverage.spatialGermanyen_US
dc.date.accessioned2019-02-20T08:17:35Z
dc.date.issued2019-06en_US
dc.identifierhttps://www.ncbi.nlm.nih.gov/pubmed/30328539en_US
dc.identifier10.1007/s00520-018-4510-9en_US
dc.identifier.citationSupport Care Cancer, 2019, 27 (6), pp. 2285 - 2293en_US
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/3072
dc.identifier.eissn1433-7339en_US
dc.identifier.doi10.1007/s00520-018-4510-9en_US
dc.description.abstractOBJECTIVE: To assess the association between gastro-intestinal (GI) symptoms and health-related quality of life (HRQoL) in ovarian cancer (OC) survivors. METHODS: Women diagnosed with OC between 2000 and 2010 as registered in the Netherlands cancer registry (n = 348), received a questionnaire on socio-demographic characteristics, HRQoL (EORTC-QLQ-C30), ovarian cancer-specific symptoms including GI (EORTC-QLQ OV28), and psychological distress (HADS). Data collection took place in 2012. RESULTS: Of 348 women diagnosed with ovarian cancer, 191 (55%) responded. Of all participants, 69% were eligible for analysis (n = 131). In 25% of all women, high level GI symptoms occurred (n = 33). In 23% of all women, recurrence of OC occurred (n = 30). Regression analysis showed that presence of high levels of GI symptoms during survivorship was associated with lower functioning on all HRQoL domains (except for emotional functioning), more symptoms, and higher levels of distress. QoL was negatively affected in those who had few and high levels of GI symptoms. QoL of those with recurrent disease was worse than those without recurrent disease. CONCLUSION: A substantial proportion of OC survivors experience GI symptoms, regardless of the recurrence of disease. Health care professionals should be aware of GI symptoms during survivorship in order to refer their patients for supportive care interventions to reduce symptoms or help survivors to cope. Further research should examine the cause of GI symptoms during OC survivorship among those with non-recurrent disease.en_US
dc.format.extent2285 - 2293en_US
dc.languageengen_US
dc.language.isoengen_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.subjectGastro-intestinal symptomsen_US
dc.subjectOvarian canceren_US
dc.subjectSurvivorshipen_US
dc.titlePresence of gastro-intestinal symptoms in ovarian cancer patients during survivorship: a cross-sectional study from the PROFILES registry.en_US
dc.typeJournal Article
dcterms.dateAccepted2018-10-09en_US
rioxxterms.versionofrecord10.1007/s00520-018-4510-9en_US
rioxxterms.licenseref.startdate2019-06en_US
rioxxterms.typeJournal Article/Reviewen_US
dc.relation.isPartOfSupport Care Canceren_US
pubs.issue6en_US
pubs.notesNot knownen_US
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Clinical Studies
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Clinical Studies/Clinical and Translational Sarcoma
pubs.publication-statusPublisheden_US
pubs.volume27en_US
pubs.embargo.termsNot knownen_US
icr.researchteamClinical and Translational Sarcomaen_US
dc.contributor.icrauthorHusson, Olgaen_US


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