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Synthesis of trisubstituted pyrimidines by regioselective S<sub>N</sub>Ar and Suzuki reactions of polyhalopyrimidines

dc.contributor.authorLarge, JM
dc.contributor.authorClarke, M
dc.contributor.authorWilliamson, DM
dc.contributor.authorMcDonald, E
dc.contributor.authorCollins, A
dc.date.accessioned2016-12-12T13:37:09Z
dc.date.issued2006-04-04
dc.identifierhttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000236788600011&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=d4b848928d1c3e5c86d298abb68475f9
dc.identifier.citationSYNLETT, 2006, (6), pp. 861 - 864 (4)
dc.identifier.issn0936-5214
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/322
dc.identifier.eissn1437-2096
dc.identifier.doi10.1055/s-2006-939050
dc.description.abstractAn efficient, regioselective approach to the synthesis of trisubstituted pyrimidines was developed. Sequential functionalization of com. available polyhalopyrimidines provided the target compds. in moderate to good overall yields.
dc.format.extent861 - 864 (4)
dc.languageeng
dc.language.isoeng
dc.publisherGEORG THIEME VERLAG KG
dc.subjectScience & Technology
dc.subjectPhysical Sciences
dc.subjectChemistry, Organic
dc.subjectChemistry
dc.subjectregioselectivity
dc.subjectpalladium
dc.subjectpyrimidine
dc.subjectSuzuki
dc.subjectcross-coupling
dc.subjectCROSS-COUPLING REACTIONS
dc.subjectRAPID ANALOG SYNTHESES
dc.subjectARYL CHLORIDES
dc.subjectDERIVATIVES
dc.subjectCATALYSTS
dc.subjectACIDS
dc.titleSynthesis of trisubstituted pyrimidines by regioselective S<sub>N</sub>Ar and Suzuki reactions of polyhalopyrimidines
dc.typeJournal Article
dcterms.dateAccepted2006-03-13
rioxxterms.versionofrecord10.1055/s-2006-939050
rioxxterms.licenseref.startdate2006-04-04
rioxxterms.typeJournal Article/Review
dc.relation.isPartOfSYNLETT
pubs.issue6
pubs.notesNot known
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics/Medicinal Chemistry 2
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics/Medicinal Chemistry 2
pubs.publication-statusPublished
pubs.embargo.termsNot known
icr.researchteamMedicinal Chemistry 2
dc.contributor.icrauthorCollins, Ian


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