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dc.contributor.authorPoort, H
dc.contributor.authorPeters, MEWJ
dc.contributor.authorGielissen, MFM
dc.contributor.authorVerhagen, CAHHVM
dc.contributor.authorBleijenberg, G
dc.contributor.authorvan der Graaf, WTA
dc.contributor.authorWearden, AJ
dc.contributor.authorKnoop, H
dc.date.accessioned2016-12-19T15:10:03Z
dc.date.issued2016-09
dc.identifier.citationJournal of pain and symptom management, 2016, 52 (3), pp. 336 - 344
dc.identifier.issn0885-3924
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/344
dc.identifier.eissn1873-6513
dc.identifier.doi10.1016/j.jpainsymman.2016.02.017
dc.description.abstractContext Informal caregivers (ICs) are increasingly involved in the monitoring of symptoms during advanced cancer patients' treatment with palliative intent. A common but subjective symptom during this extended treatment phase is fatigue.Objectives This exploratory longitudinal study aimed to determine agreement between patients and ICs about patients' fatigue severity. In addition, predictors of agreement over time were studied.Methods A sample of 107 patients with advanced cancer (life expectancy ≥ six months) and their ICs completed the subscale fatigue severity of the Checklist Individual Strength based on the patient's status at baseline and six months later. This eight-item subscale has a validated cutoff to determine the presence of clinically relevant levels of fatigue. ICs' own fatigue severity, strain, self-esteem, and relationship satisfaction were examined as predictors of agreement.Results A total of 107 dyads completed measures at baseline and 69 dyads six months later. At baseline, ICs' significantly overestimated patients' fatigue severity (P < 0.001) with a moderate amount of bias (Cohen's d = 0.48). In 81 of the 107 dyads (76%), there was congruence about the presence or absence of severe fatigue. On a group level, congruence did not significantly change over time. On a dyad level, there was a tendency to either remain congruent or reach congruence. Next to baseline congruence, ICs' fatigue severity and strain predicted ICs' fatigue ratings (R(2) = 0.22).Conclusion Most ICs accurately predict presence or absence of clinically relevant levels of patients' fatigue. ICs' own fatigue severity and strain should be taken into account as they influence agreement.
dc.formatPrint-Electronic
dc.format.extent336 - 344
dc.languageeng
dc.language.isoeng
dc.subjectHumans
dc.subjectNeoplasms
dc.subjectFatigue
dc.subjectTerminal Care
dc.subjectSeverity of Illness Index
dc.subjectLongitudinal Studies
dc.subjectTime Factors
dc.subjectAdult
dc.subjectAged
dc.subjectAged, 80 and over
dc.subjectMiddle Aged
dc.subjectCaregivers
dc.subjectFemale
dc.subjectMale
dc.subjectDiagnostic Self Evaluation
dc.titleFatigue in Advanced Cancer Patients: Congruence Between Patients and Their Informal Caregivers About Patients' Fatigue Severity During Cancer Treatment With Palliative Intent and Predictors of Agreement.
dc.typeJournal Article
dcterms.dateAccepted2016-02-29
rioxxterms.versionofrecord10.1016/j.jpainsymman.2016.02.017
rioxxterms.licenseref.startdate2016-09
rioxxterms.typeJournal Article/Review
dc.relation.isPartOfJournal of pain and symptom management
pubs.issue3
pubs.notesNot known
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Clinical Studies
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Clinical Studies/Clinical and Translational Sarcoma
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Clinical Studies
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Clinical Studies/Clinical and Translational Sarcoma
pubs.publication-statusPublished
pubs.volume52
pubs.embargo.termsNot known
icr.researchteamClinical and Translational Sarcomaen_US
dc.contributor.icrauthorvan der Graaf, Wilhelminaen


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