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dc.contributor.authorPDBe-KB consortium
dc.date.accessioned2020-05-21T11:01:41Z
dc.date.issued2020-01
dc.identifier.citationNucleic acids research, 2020, 48 (D1), pp. D344 - D353
dc.identifier.issn0305-1048
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/3618
dc.identifier.eissn1362-4962
dc.identifier.doi10.1093/nar/gkz853
dc.description.abstractThe Protein Data Bank in Europe-Knowledge Base (PDBe-KB, https://pdbe-kb.org) is a community-driven, collaborative resource for literature-derived, manually curated and computationally predicted structural and functional annotations of macromolecular structure data, contained in the Protein Data Bank (PDB). The goal of PDBe-KB is two-fold: (i) to increase the visibility and reduce the fragmentation of annotations contributed by specialist data resources, and to make these data more findable, accessible, interoperable and reusable (FAIR) and (ii) to place macromolecular structure data in their biological context, thus facilitating their use by the broader scientific community in fundamental and applied research. Here, we describe the guidelines of this collaborative effort, the current status of contributed data, and the PDBe-KB infrastructure, which includes the data exchange format, the deposition system for added value annotations, the distributable database containing the assembled data, and programmatic access endpoints. We also describe a series of novel web-pages-the PDBe-KB aggregated views of structure data-which combine information on macromolecular structures from many PDB entries. We have recently released the first set of pages in this series, which provide an overview of available structural and functional information for a protein of interest, referenced by a UniProtKB accession.
dc.formatPrint
dc.format.extentD344 - D353
dc.languageeng
dc.language.isoeng
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.subjectPDBe-KB consortium
dc.subjectProteins
dc.subjectPeer Review, Research
dc.subjectInternet
dc.subjectUser-Computer Interface
dc.subjectDatabases, Protein
dc.subjectEurope
dc.subjectKnowledge Bases
dc.subjectWorkflow
dc.titlePDBe-KB: a community-driven resource for structural and functional annotations.
dc.typeJournal Article
dcterms.dateAccepted2019-10-01
rioxxterms.versionofrecord10.1093/nar/gkz853
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0
rioxxterms.licenseref.startdate2020-01
rioxxterms.typeJournal Article/Review
dc.relation.isPartOfNucleic acids research
pubs.issueD1
pubs.notesNot known
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics/Computational Biology and Chemogenomics
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics/Computational Biology and Chemogenomics
pubs.publication-statusPublished
pubs.volume48
pubs.embargo.termsNot known
icr.researchteamComputational Biology and Chemogenomicsen_US
dc.contributor.icrauthorAl-Lazikani, Bissanen


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