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dc.contributor.authorPDBe-KB consortiumen_US
dc.date.accessioned2020-05-21T11:01:41Z
dc.date.issued2020-01en_US
dc.identifier.citationNucleic acids research, 2020, 48 (D1), pp. D344 - D353en_US
dc.identifier.issn0305-1048en_US
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/3618
dc.identifier.eissn1362-4962en_US
dc.identifier.doi10.1093/nar/gkz853en_US
dc.description.abstractThe Protein Data Bank in Europe-Knowledge Base (PDBe-KB, https://pdbe-kb.org) is a community-driven, collaborative resource for literature-derived, manually curated and computationally predicted structural and functional annotations of macromolecular structure data, contained in the Protein Data Bank (PDB). The goal of PDBe-KB is two-fold: (i) to increase the visibility and reduce the fragmentation of annotations contributed by specialist data resources, and to make these data more findable, accessible, interoperable and reusable (FAIR) and (ii) to place macromolecular structure data in their biological context, thus facilitating their use by the broader scientific community in fundamental and applied research. Here, we describe the guidelines of this collaborative effort, the current status of contributed data, and the PDBe-KB infrastructure, which includes the data exchange format, the deposition system for added value annotations, the distributable database containing the assembled data, and programmatic access endpoints. We also describe a series of novel web-pages-the PDBe-KB aggregated views of structure data-which combine information on macromolecular structures from many PDB entries. We have recently released the first set of pages in this series, which provide an overview of available structural and functional information for a protein of interest, referenced by a UniProtKB accession.en_US
dc.formatPrinten_US
dc.format.extentD344 - D353en_US
dc.languageengen_US
dc.language.isoengen_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.subjectPDBe-KB consortiumen_US
dc.subjectProteinsen_US
dc.subjectPeer Review, Researchen_US
dc.subjectInterneten_US
dc.subjectUser-Computer Interfaceen_US
dc.subjectDatabases, Proteinen_US
dc.subjectEuropeen_US
dc.subjectKnowledge Basesen_US
dc.subjectWorkflowen_US
dc.titlePDBe-KB: a community-driven resource for structural and functional annotations.en_US
dc.typeJournal Article
dcterms.dateAccepted2019-10-01en_US
rioxxterms.versionofrecord10.1093/nar/gkz853en_US
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0en_US
rioxxterms.licenseref.startdate2020-01en_US
rioxxterms.typeJournal Article/Reviewen_US
dc.relation.isPartOfNucleic acids researchen_US
pubs.issueD1en_US
pubs.notesNot knownen_US
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics/Computational Biology and Chemogenomics
pubs.publication-statusPublisheden_US
pubs.volume48en_US
pubs.embargo.termsNot knownen_US
icr.researchteamComputational Biology and Chemogenomicsen_US
dc.contributor.icrauthorAl-Lazikani, Bissanen_US


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