Browsing Cancer Therapeutics by author "Kinnersley, Benjamin"
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Analysis of 10,478 cancer genomes identifies candidate driver genes and opportunities for precision oncology.
Kinnersley, B; Sud, A; Everall, A; Cornish, AJ; Chubb, D; et al. (NATURE PORTFOLIO, 2024-06-18)Tumor genomic profiling is increasingly seen as a prerequisite to guide the treatment of patients with cancer. To explore the value of whole-genome sequencing (WGS) in broadening the scope of cancers potentially amenable ... -
Leveraging Human Genetics to Guide Cancer Drug Development.
Kinnersley, B; Sud, A; Coker, EA; Tym, JE; Di Micco, P; et al. (AMER SOC CLINICAL ONCOLOGY, 2018-11-21)PURPOSE: The high attrition rate of cancer drug development programs is a barrier to realizing the promise of precision oncology. We have examined whether the genetic insights from genome-wide association studies of cancer ...