Browsing Cancer Therapeutics by author "Lepicard, Elise"
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Evaluating Imaging Biomarkers of Acquired Resistance to Targeted EGFR Therapy in Xenograft Models of Human Head and Neck Squamous Cell Carcinoma.
Baker, LCJ; Sikka, A; Price, JM; Boult, JKR; Lepicard, EY; et al. (FRONTIERS MEDIA SA, 2018-07-23)Background: Overexpression of EGFR is a negative prognostic factor in head and neck squamous cell carcinoma (HNSCC). Patients with HNSCC who respond to EGFR-targeted tyrosine kinase inhibitors (TKIs) eventually develop ... -
Hypoxia and its therapeutic possibilities in paediatric cancers.
Bernauer, C; Man, YKS; Chisholm, JC; Lepicard, EY; Robinson, SP; et al. (SPRINGERNATURE, 2021-02-02)In tumours, hypoxia-a condition in which the demand for oxygen is higher than its availability-is well known to be associated with reduced sensitivity to radiotherapy and chemotherapy, and with immunosuppression. The ...