Browsing Clinical Studies by author "Payne, Geoffrey"
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Evaluation of magnetic resonance diffusion and spectroscopy measurements as predictive biomarkers in stage 1 cervical cancer.
Payne, GS; Schmidt, M; Morgan, VA; Giles, S; Bridges, J; Ind, T; DeSouza, NM (2010-02)<h4>Objective</h4>To establish whether ADC and total choline were significantly different between cervical tumors with different histological characteristics (type, degree of differentiation, presence or absence of ... -
Noninvasive detection of carboxypeptidase G2 activity in vivo.
Jamin, Y; Smyth, L; Robinson, SP; Poon, ESC; Eykyn, TR; Springer, CJ; Leach, MO; Payne, GS (2011-05)The pseudomonad protein, carboxypeptidase G2 (CPG2), is a prodrug-activating enzyme utilized in the targeted chemotherapy strategies of antibody- and gene-directed enzyme prodrug therapy (ADEPT and GDEPT). We have developed ...