Now showing items 1-3 of 3

    • Deregulated expression of HDAC9 in B cells promotes development of lymphoproliferative disease and lymphoma in mice. 

      Gil, VS; Bhagat, G; Howell, L; Zhang, J; Kim, CH; Stengel, S; Vega, F; Zelent, A; Petrie, K (2016-12)
      Histone deacetylase 9 (HDAC9) is expressed in B cells, and its overexpression has been observed in B-lymphoproliferative disorders, including B-cell non-Hodgkin lymphoma (B-NHL). We examined HDAC9 protein expression and ...
    • JMJD6 Is a Druggable Oxygenase That Regulates AR-V7 Expression in Prostate Cancer 

      Paschalis, A; Welti, J; Neeb, AJ; Yuan, W; Figueiredo, I; Pereira, R; Ferreira, A; Riisnaes, R; Rodrigues, DN; Jimenez-Vacas, JM; Kim, S; Uo, T; Di Micco, P; Tumber, A; Islam, MS; Moesser, MA; Abboud, M; Kawamura, A; Gurel, B; Christova, R; Gil, VS; Buroni, L; Crespo, M; Miranda, S; Lambros, MB; Carreira, S; Tunariu, N; Alimonti, A; Al-Lazikani, B; Schofield, CJ; Plymate, SR; Sharp, A; de Bono, JS (AMER ASSOC CANCER RESEARCH, 2021-02-15)
    • Targeting p300/CBP axis in lethal prostate cancer. 

      Welti, J; Sharp, A; Brooks, N; Yuan, W; McNair, C; Chand, SN; Pal, A; Figueiredo, I; Riisnaes, R; Gurel, B; Rekowski, J; Bogdan, D; West, W; Young, B; Raja, M; Prosser, A; Lane, J; Thomson, S; Worthington, J; Onions, S; Shannon, J; Paoletta, S; Brown, R; Smyth, D; Harbottle, GW; Gil, VS; Miranda, S; Crespo, M; Ferreira, A; Pereira, R; Tunariu, N; Carreira, S; Neeb, AJ; Ning, J; Swain, A; Taddei, D; International Dream Team, SUTC-P; Schiewer, MJ; Knudsen, KE; Pegg, N; de Bono, JS (2021-01-11)
      Resistance to androgen receptor (AR) blockade in castration resistant prostate cancer (CRPC) is associated with sustained AR signaling, including through alternative splicing of the AR (AR-SV). Inhibitors of transcriptional ...