Browsing Clinical Studies by author "Coleman, Niamh"
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Detection of circulating tumour cell clusters in human glioblastoma.
Krol, I; Castro-Giner, F; Maurer, M; Gkountela, S; Szczerba, BM; et al. (NATURE PUBLISHING GROUP, 2018-08-14)Human glioblastoma (GBM) is a highly aggressive, invasive and hypervascularised malignant brain cancer. Individual circulating tumour cells (CTCs) are sporadically found in GBM patients, yet it is unclear whether multicellular ... -
Safety, efficacy and survival of patients with primary malignant brain tumours (PMBT) in phase I (Ph1) trials: the 12-year Royal Marsden experience.
Coleman, N; Michalarea, V; Alken, S; Rihawi, K; Lopez, RP; et al. (SPRINGER, 2018-08-01)BACKGROUND: Primary malignant brain tumours (PMBT) constitute less than 2% of all malignancies and carry a dismal prognosis. Treatment options at relapse are limited. First-in-human solid tumour studies have historically ...